Kaohsiung Medical University

Bai-Luh Wei

Chun-Nan Lin

Shyh-Chyun Yang

Huang-Yao Tu

Chi-Feng Hung

Dravidum Maitraie

Jih-Pyang Wang

Ya-Ting Liou

A-Mei Huang

Shen-Jeu Won

Tzyh-Chyuan Hour

Yeong-Shiau Pu

Kim-Hong Gan

The present invention provides a chemical compound having the structure being one selected from a group consisting of wherein Ris one selected from a group consisting of COOCH, COOCHPh, CONHCH(CH)and CONHCH, Ris one selected from a group consisting of H, CHand CH(CH), Ris one selected from a group consisting of H, CH, CH(CH)and CHPh, and Ris one of CH(CH)and CH.

18&#x3b2;-Glycyrrhetinic acid derivatives and synthetic method thereof

Several ursolic acid derivatives and pharmaceutical compositions thereof are provided. The ursolic acid derivatives and the pharmaceutical compositions thereof have at least one of an anticancer and an anti-inflammatory effects. A method for increasing a reactive oxygen species in a cell is also provided. The method comprises a step of providing the cell with a pharmaceutical composition including an ursolic acid derivative.

Ursolic acid derivative and pharmaceutical composition thereof

The present invention provides a chemical compound having the structure being one selected from a group consisting of  wherein Ris one selected from a group consisting of COOCH, COOCHPh, CONHCH(CH)and CONHCH, Ris one selected from a group consisting of H, CHand CH(CH), Ris one selected from a group consisting of H, CH, CH(CH)and CHPh, and Ris one of CH(CH)and CH.

18&#x3b2;-glycyrrhetinic acid derivatives and synthetic method thereof

Growing community of inventors

Kaohsiung, Taiwan

Bai-Luh Wei