Sabanci Üniversitesi

Bahattin Koç

Navid Khani

Ali Nadernezhad

Saime Burçe Özler

Can Küçükgül

Saime Burce ÖZler

Can Kücukgül

A method for automatic printing of a three dimensional heterogeneous structure in accordance with a computer-aided design procedure, including the steps of: aspirating a first portion consisting of a first material (M1) in liquid form, from a first liquid container into a capillary (C); aspirating a second portion consisting of a second material (M2) in liquid form different than the first material (M1), from a second liquid container into said capillary (C), such that the first portion and the second portion constitute longitudinally different parts of a longitudinally heterogeneous filament (F) encompassed by the capillary (C); and extraction of the filament (F) from the capillary (C) thus laying it as a portion of a printed layer.

Method for three dimensional printing of heterogeneous structures

A network () for replacement of a living tissue, said network is a scaffold-free artificial hollow biological tissue network comprising a plurality of longitudinal multicellular aggregates () arranged in a plurality of bioprinted layers () which are located on top of one another, further comprising an inner surface () and an outer surface (), wherein at least one of said bioprinted layers () is in shape of a planar closed loop such that a conduit for conveying fluids is defined, and said longitudinal multicellular aggregate () is a mixture of at least two cell types. Also a method for obtaining said longitudinal multicellular aggregate, and a further method for biomodeling and planning said network are proposed.

Artificial hollow biological tissue network and method for preparation thereof

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Istanbul, Turkey

Bahattin Koç