Dr. Reddy's Laboratories, Incorporated

Babu Ireni

Srinivas Polavarapu

Pratap Reddy Padi

Ranga Reddy Vangala

Vijaya Anand Ramasamy

Shailaja Padamata

Kavitha Nerella

Javed Iqbal

Srinivas Katkam

Srinivas Oruganti

Krishna Vinigari

Rajasekhar Kadaboina

Bhaskar Kandagatla

Rajeswar Reddy Sagyam

Buchi Reddy Reguri

Suresh Kumar Ramdoss

Srinivas Reddy Gade

Srinivasulu Rangineni

Arjunkumar Tummala

Raghavendar Rao Morthala

The present application provide processes for the preparation of fingolimod and its pharmaceutically acceptable salts, process for the purification of fingolimod hydrochloride and process for the preparation of amorphous fingolimod hydrochloride.

Preparation of fingolimod and its salts

There is provided a process for preparation of sitagliptin of Formula II or a pharmaceutically acceptable salt thereof by deprotection of Formula IX. 

Processes for the preparation of sitagliptin and pharmaceutically acceptable salts thereof

There is provided an improved process for the preparation of Sitagliptin of Formula II by reduction of compound of Formula VIII to Formula IX followed by deprotection of Formula IX to afford Sitagliptin of Formula II.

There is provided a process for preparation of a monoketal compound of the structure that includes reacting 1,4-cyclohexanedione of the structure with a diol of the structure in a halogenated organic solvent in the presence of an acid catalyst, wherein X is a substituted or unsubstituted ethylene or propylene. Various embodiments and variants are provided.

Process for the preparation of monoketals of 1,4-cyclohexanedione including 1, 4-cyclohexanedione mono-2,2-dimethyl trimethylene ketal

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Babu Ireni