University of Nebraska

King Abdulaziz University

Azadeh Mostafavi

Tyrell Williams

Numan Abdullah Salah

Adnan Memic

Tuerdimaimaiti Abudula

Ali Tamayol

Ammar Abdulghani Melaibari

Carina Russell

Asija Memic

Mohammed Shaaban Abdelwahab

Mehdi Kazemzadeh Narbat

Indranil Sinha

Jacob Quint

Ahmed Salem AlShahrie

Systems and methods are described that utilize bioprinters to form scaffold structures in situ to facilitate treatment of the musculoskeletal or skin disorders in patients. A method for treating a musculoskeletal disorder of a patient includes positioning a bioprinter at a situs of the musculoskeletal disorder, or a situs of a skin injury, in the patient. The method includes extruding a hydrogel formulation from the bioprinter into the situs. The method includes curing the hydrogel formulation in the situs. The hydrogel formulation has a composition effective to generate, upon the curing, a scaffold structure in the situs to facilitate muscle hypertrophy and/or new muscle fibers, or skin wound healing, in the situs.

Bioprinter devices, systems and methods for printing soft gels for the treatment of musculoskeletal and skin disorders

A filament or printing material placed in a syringe for 3D printing comprising polymers, proteins, and/or functional particles and materials is provided. Methods of treating a bone defect in a subject in need thereof comprising using a handheld 3D printer to apply a filament or the printing material placed in a syringe to the bone defect of the subject are also provided. Methods of fixing or gluing natural or synthetic bone grafts using a handheld 3D printer to apply a filament or the printing material placed in a syringe over and around the defect or at the interface of a flap and the bone. Methods of printing a graft cage for retaining bone grafts and/or bone graft substitute in its desired location during healing for treatment of critical-sized segmental defects in long bones are provided.

3D printing of polymeric bioceramics for the treatment of bone defects

Growing community of inventors

Lincoln, NE, United States of America

Azadeh Mostafavi