Astellas Pharma Gmbh

Wakunaga Pharmaceutical Co., Ltd.

Fujisawa Pharmaceutical Company, Ltd.

Ayako Toda

Hidenori Ohki

Toshio Yamanaka

Kohji Kawabata

Satoshi Inoue

Shinya Okuda

Kenji Murano

Hiroaki Mizuno

Kenji Itoh

Keiji Misumi

Hiroshi Matsuda

Keiji Matsuda

Takashi Ogino

Shigeki Kunikawa

Takuya Makino

Hiroaki Ohtake

Junya Ishida

David Barrett

Yu Harayama

Takahiro Matsuya

Kenji Satoh

Kenji Sato

Masaru Ohgaki

Masaru Oogaki

The present invention relates to a new cyclic peptide compound or a salt thereof, which has anti-hepatitis C virus activities based on inhibitory activity against the RNA replication of hepatitis C virus replicon, a process for preparation thereof, a pharmaceutical composition comprising the same, and a method for prophylactic and/or therapeutic treatment of hepatitis C in a human being or an animal.

Cyclic peptide compounds

The present invention relates to a compound of the formula [I]:  

Cephem compounds

The present invention relates to a compound of the formula [I]: wherein 

This invention relates to new polypeptide compound represented by the general formula (I) wherein R, R, R, R, Rand Rare as defined in the description or a salt thereof which has antimicrobial activities (especially, antifungal activities), inhibitory activity on &#x3b2;-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases includinginfection (e.g.pneumonia) in a human being or an animal.

Cyclic hexapeptide derivatives

Growing community of inventors

Osaka, Japan

Ayako Toda