Ajinomoto Co., Ltd.

Ayako Sasahara

Takayuki Ito

Hiroyuki Nozaki

Shunichi Suzuki

Tatsuki Kashiwagi

Uno Tagami

Hideyuki Suzuki

Eri Tabuchi

A microorganism useful as an expression host for &#x3b3;-Glu-Val synthetase and a method for producing &#x3b3;-Glu-Val-Gly using &#x3b3;-Glu-Val synthetase expressed in the microorganism are provided. By using &#x3b3;-Glu-Val synthetase expressed in a bacterium, such asbacteria, modified so that the activity of a protein encoded by a ybdK gene (YBDIQ is reduced as an expression host, &#x3b3;-Glu-Val-Gly is produced (Yom Glu, Val, and Gly as raw materials.

Microorganism and method for producing gamma-glutamyl-valyl-glycine

A mutant glutamate-cysteine ligase (GSHA) suitable for generating &#x3b3;-Glu-Val, and a method for producing &#x3b3;-Glu-Val-Gly using the same are provided. &#x3b3;-Glu-Val is produced by using a mutant GSHA having a specific mutation with Glu and Val as raw materials, and &#x3b3;-Glu-Val-Gly is further produced by using &#x3b3;-Glu-Val and Gly as raw materials. &#x3b3;-Glu-Val-Gly is produced by using a mutant GSHA having a specific mutation with Glu, Val, and Gly as raw materials.

Mutant glutamate-cysteine ligase and method for manufacturing gamma glutamyl-valyl-glycine

Growing community of inventors

Kawasaki, Japan

Ayako Sasahara