University of California

Axel Visel

Arnold Kriegstein

John L R Rubenstein

Len A Pennacchio

Cory R Nicholas

Ying-Jiun (Jasmine) Chen

Daniel Vogt

Herein are described a set of novel specific human enhancers for specific forebrain cell types used to study and select for human neural progenitor cells. This approach enables the ability to generate interneurons from human ES, iPS and iN cells, making them available for human transplantation and for molecular/cellular analyzes. These approaches are also directly applicable to generating other neuronal cell types, such as cortical and striatal projection neurons, which have implications for many human diseases.

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El Cerrito, CA, United States of America

Axel Visel