Bayer Innovation Gmbh

Erlus Aktiengesellschaft

Axel Thierauf

Iwer Baecker

Andreas Haisch

Alexander Stoll

Josef Kammermaier

Manfred Rauser

Yinyuan Liu

Carsten Ackerhans

The present invention relates to a polyethoxysiloxane (PES) material to be obtained in that (a) a first hydrolysis condensation reaction of a maximum of one group X of one or more different Si compounds of the formula (I) SiX4 (I) in which the groups X are the same or different and represent hydroxy, hydrogen, or ethoxy (EtO), are catalyzed in an acidic fashion at an initial pH value of 0 to &#x2266;7, is conducted in the presence of ethanol (EtOH) or an ethanol-water mixture as a solvent over a time period of 1 to 24 hours at a temperature of 0&#xb0; C. to 78&#xb0; C, (b) a second hydrolysis condensation reaction of the material obtained in step (a) is conducted while simultaneously removing the solvent by successive evaporation in a gas diffusion-tight container at a pressure of 100 to 1013 mbar, preferably at a slight negative pressure of 300 mbar to 800 mbar and a temperature of 50-78&#xb0; C. until a drastic increase in viscosity (at a shear rate of 10 sat 4&#xb0; C.) to 0.5 to 2 Pa&#xb7;s until a constant weight is attained and a cyclotetrasiloxane of the general formula ((SiO(OH)(OEt)&#xd7; 1/64HO)and a molar mass of 4*approx. 114 g=approx. 456 g; (c) said PES material is cooled in a closed container over a time period from a few minutes to a few hours, and (d) the PES material obtained from step (c) is converted into an rPES material by a third hydrolysis condensation reaction.

Nontoxic polyethoxysiloxane material or the production of biologically resorbable and/or bioactive articles containing polyethoxysiloxane material, the production thereof, and the use thereof

Methods accelerate healing of a wound by applying a multilayer bandage to the wound. The multilayer bandage has a spun-bonded webbing comprising at least one partially or completely hydrolytically condensed silicon compound and a water-impervious or semi-permeable first membrane having at least one water-insoluble polymer. The webbing has a biologically degradable or biologically resorbable structure and is brought into direct contact with the wound by placing the webbing in or on the wound.

Method for accelerated wound healing using novel fibrous webbings

The present invention provides a multilayer bandage, having a webbing for contacting a wound and a first membrane that has at least one water-insoluble polymer and is water-impervious. The present invention further provides methods for making the multilayer bandage, methods of using the multilayer bandage for accelerated wound healing, and kits having compositions of the present invention.

Compositions and processes for accelerated wound healing using novel fibrous webbings

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Mallersdorf-Pfaffenberg, Germany

Axel Thierauf