Veb Jenapharm

Veb Berlin-Chemie

Axel Kramer

Wolfgang Weuffen

Lothar Adam

Sieghard Luck

Ulrich Burth

Hubert Rattba

Herbert Teubner

Lothar Neeb

Eberhard Schrotter

Gerhard Grubel

Rainer Muller

Ursula Albrecht

The invention relates to synergistically active mixtures for the control of phytopathogenic fungi and bacteria comprising antimicrobially effective derivatives of a phenol of the general formula ##STR1## R.sub.1, R.sub.2, R.sub.5 and R.sub.6 represent hydrogen (for R.sub.5 and R.sub.6 only), bromine, chlorine or alkyl with up to 5 C-atoms, R.sub.3 represents hydrogen, sodium, potassium, calcium, barium or ammonium*, magnesium, bismuth, tin, zinc or copper, furthermore R.sub.1, R.sub.2 and R.sub.3 may be interchangeably positioned in the ortho position as well as in the para position, and using fungicides. Benzimidazole fungicides or dithiocarbamates are predominantly used preferably on potato tubers with carbendazim and thiabendazole as mixing components.

Compositions for combatting phytopathogenical fungi and bacteria

A method is provided for the production of antimicrobially effective phenol derivatives according to general Formula I in which R.sub.1 is bromine or chlorine, R.sub.2 is methyl or ethyl, R.sub.3 is hydrogen or sodium, potassium, ammonium or by alkyl with up to 10 C-atoms substituted ammonium, magnesium, calcium, barium, aluminum, tin, bismuth, copper, zinc, R.sub.4 and R.sub.5 are independently hydrogen, alkyl or alkoxy with up to 5 C-atoms, bromine or chlorine. The compounds are obtained by benzylation of 6-halogen- or 4-halogen-2-alkylphenol, halogenation of 2-alkyl-4-benzylphenol or -6-benzylphenol, or by alkylation of 6-halogen-4-benzylphenol or of 4-halogen-6-benzylphenol and if necessary through reaction of the product with hydroxide, alcoholate, carbonate or hydrogen carbonate of the above-mentioned metals. Water or lipid soluble effective substances are obtained which display a broad antimicrobial activity spectrum.

Antimicrobially effective derivatives of phenol and methods for their

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Greifswald, Germany

Axel Kramer