Asceneuron Sa

Awadut Gajendra Giri

Anna Quattropani

Santosh Shripad Kulkarni

David Malcolm Crowe

Dawn V Toronto

Paul Rakesh

Santosh S Kulkarni

Johannes Nicolaas Koek

Grant Wishart

Robert Hett

The invention relates to acid addition salts of piperazine derivatives, as well as solid forms, such as polymorphic forms, thereof, which are useful as pharmaceutical ingredients and, in particular, as glycosidase inhibitors.

Acid addition salts of piperazine derivatives

The invention relates to succinic acid addition salts or fumaric acid addition salts of piperazine derivatives of formula (I), as well as solid forms, such as polymorphic forms, thereof, which are useful as pharmaceutical ingredients and, in particular, as glycosidase inhibitors.

Succinate and fumarate acid addition salts of piperazine derivatives

The disclosure relates to compounds of formula (I) useful in the treatment of tauopathies and Alzheimer's disease wherein A, R, W, Q, n, and m are described herein.

Glycosidase inhibitors

Compounds of formula (I), wherein A, R, W, Q, n, and m have the meaning according to the claims, can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease.

Sulfoximine glycosidase inhibitors

Compounds of formula (I'), wherein A, R, R, T, T, T, T, L, W, Z, R&#x2032;&#x2033;, m and n have the meaning according to the claims, can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease.

Tetrahydro-benzoazepine glycosidase inhibitors

Compounds of formula (I), wherein A, R, L, Z, Q, Qand n have the meaning according to the claims, can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease.

Spiro compounds as glycosidase inhibitors

Compounds of formula (I), wherein A, R, W, Q, n and m have the meaning according to the claims, can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease. 

Compounds of formula (I), wherein A, R, W, W, W, W, W, W, L, Q, Rand u have the meaning according to the claims, can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease. 

Annulated glycosidase inhibitors

Compounds of formula (I), wherein A, R, W, Q, n, and m have the meaning according to the claims, can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease. 

Compounds of formula (I), wherein A, R, W, Q, L, n and m have the meaning according to the claims, can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease. 

Linear glycosidase inhibitors

Compounds of formula (I), wherein R', R&#x2033;, R, X, W, Q, n, and m have the meaning according to the claims, can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease. 

Substituted dihydrobenzofuran glycosidase inhibitors

Compounds of formula (I) wherein A, R, W, Q, n and m have the meaning according to the claims can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease. 

Growing community of inventors

Bengaluru, India

Awadut Gajendra Giri