Ultima Genomics, Inc.

Apm Automation Solutions Ltd

Rosemount Inc.

Applied Materials Israel Limited

Avishai Bartov

Gilad Almogy

Yossi Zlotnick

Mark Pratt

Steven Menchen

Nathan Beckett

Jürgen Frosien

Jamie Michael Sullivan

Kristopher Barbee

Denis Pristinski

Dumitru Brinza

Abizar Lakdawalla

Derek Schulte

Mark Geshel

Ron Naftali

Haim Feldman

Juergen Frosien

Pavel Adamec

Mark Wagner

Boris Golberg

Gadi Greenberg

Helmut Banzhof

Yoav Etzioni

Ophir Gvirtzer

Lior Shoval

Michael Ben Yishai

Provided are systems and methods for analyte detection and analysis. A system can comprise an open substrate configured to rotate. The open substrate can comprise an array of immobilized analytes. A solution comprising a plurality of probes may be directed, via centrifugal force, across the array during rotation of the substrate, to couple at least one of the plurality of probes with at least one of the analytes to form a bound probe. A detector can be configured to detect a signal from the bound probe via continuous rotational area scanning of the substrate.

Methods and systems for analyte detection and analysis

A polarizer system is described. The polarizer system comprises at least one polarization beam splitter, a polarization rotator, and a beam combiner. The at least one polarization beam splitter is positioned to receive input radiation beam and to split the input radiation beam directing a first beam portion having a first linear polarization orientation along a first path and a second beam portion having a second linear polarization orientation orthogonal to said first linear polarization orientation along a second path. The polarization rotator is located along said second path and configured to rotate polarization of said beam portion to be parallel to said first linear polarization orientation. The beam combiner is configured and positioned to combine said first and second beam portions to form a common beam having said first linear polarization orientation propagating along a selected optical path.

Polarization optical system

The present disclosure provides methods and systems for accurate and efficient context-aware base calling of sequences. In an aspect, disclosed herein is a method for sequencing a nucleic acid molecule, comprising: (a) sequencing the nucleic acid molecule to generate a plurality of sequence signals; and (b) determining base calls of the nucleic acid molecule based at least in part on (i) the plurality of sequence signals and (ii) quantified context dependency for at least a portion of the plurality of sequence signals.

Methods and systems for sequence calling

An ultrawide band two-way ranging based positioning system includes a number of active tags each having a position, and a number of beacons configured for location of a position of a tag of the plurality of active tags. The active tags and the beacons are synchronized continuously to a common time base.

Positioning system

The present disclosure provides methods, systems, and media for accurate and efficient estimation of a genome of a genus.

A positioning system, includes a plurality of anchor stations each configured to transmit a radio frequency signal. A mobile station includes a radio frequency transceiver configured to transmit and receive a radio frequency signal from at least one of the plurality of anchor stations. A processing unit is configured to determine position information of the mobile unit based upon the transmitted and received radio frequency signal. Another positioning system uses a number of beacons ranging a number of mobile tags with ultra-wide band ranging, and communicating wirelessly with an application server.

Provided are methods for biological sample processing and analysis. A method can comprise providing a substrate configured to rotate. The substrate can comprise an array having immobilized thereto a biological analyte. A solution comprising a plurality of probes may be directed, via centrifugal force, across the substrate during rotation of the substrate, to couple at least one of the plurality of probes with the biological analyte. A detector can be configured to detect a signal from the at least one probe coupled to the biological analyte, thereby analyzing the biological analyte.

Methods for biological sample processing and analysis

Provided are systems for biological sample processing and analysis. A system can comprise a substrate configured to rotate. The substrate can comprise an array configured to immobilize a biological analyte. A fluid flow unit comprising a fluid channel can be configured to dispense a solution comprising a plurality of probes. The solution may be directed, via centrifugal force, across the substrate during rotation of the substrate, to couple at least one of the plurality of probes with the biological analyte. A detector in optical communication with the array can be configured to detect one or more signals from the at least one probe coupled to the biological analyte.

Systems for biological sample processing and analysis

Growing community of inventors

Hod-Hasharon, Israel

Avishai Bartov