Perkinelmer Las, Inc.

Perkinelmer Instruments LLC

Perkinelmer Health Sciences, Inc.

The Perkin-Elmer Corporation

Avinash Dalmia

Otto J Prohaska

Andrew Tipler

David J Clark

E Joel McCorkle

John McCaffrey

Michael J Rafa

David Jerry Scott

Paul L St Cyr

James Botelho

John Vanderhoef

Paul E Schallis

Neal Green

Paul G Saviano

Giuseppe Coppola

Donald L Groeschner

Gitesh Kumar

Mario Carozza

Guiseppe Coppola

John Mccaffrey

Joel E Mccorkle

Michael Rafa

Paul Schallis

This disclosure provides quantitative, rapid, and reliable LC-MS/MS methods for analyzing panels of pesticides and mycotoxins in various samples, including very hydrophobic and chlorinated compounds normally analyzed on a GC-MS/MS system. The methods can be carried out using a single instrument and can detect and quantify levels of the pesticides and mycotoxins that are well below action limits specified by U.S. states (e.g., California) and other countries (e.g., Canada) for these compounds inproducts.

Systems and methods for pesticide detection using mass spectroscopy

A gas chromatography system comprising a sample introduction device, an oven coupled to the sample introduction device and a detector coupled to the oven is disclosed. In certain examples, the oven may be configured to receive a chromatography column in a space in the oven. In some examples, the oven may be constructed and arranged to provide a substantially constant temperature to the space during an analysis stage of the gas chromatography system.

Methods and devices for circulating air

Certain aspects and examples are directed to sorbent devices and methods of using them. In certain embodiments, a sorbent device comprising a body comprising a sampling inlet, a base and a longitudinal diffusion path between the inlet and the base is provided. In some embodiments, the sorbent device can include at least two sorbent materials fluidically coupled to the longitudinal diffusion path, in which the sorbent materials are arranged from a material with a weakest sorbent strength to a material with a strongest sorbent strength with the weakest sorbent strength material adjacent to the sampling inlet.

Sorbent devices with longitudinal diffusion paths and methods of using them

The invention relates to an electrochemical sensor and method for providing the sensor having an insulator, an electrode deposited on the insulator, an electrolytic material in contact with the electrode for providing an electrical connection, and a cooling and heating element in contact with the insulator and spaced apart from the electrode for adjusting a temperature of the sensor.

Method and apparatus for providing an electrochemical sensor at an elevated temperature

The present teachings relate to systems and methods for oxidizing a sensor having a substrate, an electrode in contact with the substrate, and an electrolytic material in contact with the electrode, where oxidizing includes applying an oxidizing potential (between approximately 350 mV and 700 mV) to the electrode. In some embodiments, the methods and systems include hydrating the sensor by applying a hydrating potential (between approximately 0 mV and &#x2212;500 mV) to the electrode. In some embodiments, the applied potential can vary cyclically between an oxidizing and hydrating potential.

Method and apparatus for improving the performance of an electrochemical sensor

The invention relates to an electrochemical gas sensor having both a reference sensor and an active sensor, whereby each reference and active sensor includes a substrate, a counter electrode deposited on a surface of the substrate, a sensing electrode also deposited on the surface, and a solid electrolytic material in electrical contact with both electrodes for carrying a flow of ions between them, which measures a concentration of a gas and compensates for relative humidity differences between sample gas and surrounding atmosphere. The sensor also includes a layer of solid electrolytic material on the sensing electrode of the reference sensor and a film of solid electrolytic material on the sensing electrode of the active sensor, whereby the layer is thicker than the film. The invention may further include a reference electrode in both the reference and active sensors for improving sensor accuracy and/or repeatability.

Electrochemical sensor compensated for relative humidity

The invention relates to an electrochemical gas sensor having a substrate, substrate surface for depositing electrodes thereon, counter and sensing electrodes for measuring current flow, an electrolyte for providing an electrical connection between the electrodes, and an electrode surface having minimal porosity, pore size, and thickness for deterring flooding.

Electrochemical sensor having nonporous working electrode

The invention relates to a method and apparatus for providing a reactor having a heater, a passage for transporting a reactant, and a chamber containing a gas sample and being coupled to the passage for receiving the reactant and mixing the reactant with the gas sample. The reactor further includes a connector leading from the chamber to the heater for transporting a mixture of the reactant and gas sample, and wherein the heater heats the mixture of the reactant and gas sample.

Method and apparatus for improved gas detection

The invention relates to an electrochemical gas generator including a substrate for providing a surface for electrode deposition, a first electrode deposited on the surface for providing an electrical connection with a conducting medium, a second electrode deposited on the substrate for generating a gas, and a plurality of members extending from at least one side of the first electrode placed alternately with a plurality of extensions protruding from at least one side of the second electrode for improving generator efficiency.

Interdigitated electrochemical gas generator

The invention relates to an electrochemical gas sensor having improved response time and sensitivity. The electrochemical gas sensor includes a substrate for providing a surface upon which a film of conductive material may be deposited, a pair of electrodes deposited on the substrate for permitting a measurement of current, and an electrolytic material for providing an electrical connection between the electrodes. The electrochemical gas sensor further includes a passage in the surface for holding or transporting gas received from a gas source, whereby sensing occurs at a three way interface where the gas, electrolytic material, and electrodes come in direct contact with one another.

Electrochemical gas sensor with passage for receiving gas

A miniaturized gas sensor comprised of film type electrodes, on a non-conductive supportive substrate, and in contact with a dry ionomer electrolyte, for detection of toxic gases, i.e., carbon monoxide, and other oxidizable or reducible gases and vapors and method of making same is described. The all-solid planar sensor cell has two or more film type electrodes arranged on a non-conductive planar surface of a supportive substrate. Manufacturing the electrochemical sensor with dry ionomer prevents electrode flooding and allows for improved response time upon assembly. The sensor cell contains no liquid electrolyte and is operated in a constant-voltage, potentiostatic or potentiodynamic mode. A high sensitivity to a select gas or vapor is achieved by a three-phase contact area design for a sensing electrode, which provides contact with the solid ionomer electrolyte, as well as the gas sample via diffusion openings or holes that penetrate through the supportive substrate.

Electrochemical sensor with dry ionomer membrane and methodfor making the same

The invention relates to a method and apparatus for determining a total concentration of a component in a sample, including a reactor for oxidizing or reducing the sample, a chromatographic column coupled to the reactor for separating the component in the sample, and an electrochemical gas sensor coupled to the chromatographic column for detecting the component. In further embodiments, a filter may be used instead of or in addition to the column. Moreover, multiple sensors may be used instead of or in addition to the column for simultaneously detecting multiple components.

Growing community of inventors

Hamden, CT, United States of America

Avinash Dalmia