Technion Research & Development Foundation Ltd

Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.

University of Utah Research Foundation

Yeda Research and Develpment & Co. Ltd

Hadasit Medical Research Services and Development Ltd.

Barcode Diagnostics Ltd.

Avi Schroeder

Jacob Klein

Ronit Goldberg

Joshua Schiffman

Yechezkel Barenholtz

Zvi Yaari

Lisa Abegglen

Yechezkel Barenholz

Ronen Eavri

Izhak Etsion

Havazelet Bianco-Peled

Assaf Yosef Zinger

Sarit Sivan

Raphael Tshuva

Annie Sabbah

Felix Badinter

Shlomit Avidan-Shlomovich

Yarden Degani

Dorit Nitzan

Mor Goldfeder

Grigory Halperin

Dorrit Nitzan

The invention provides a method for lubricating one or more surfaces, comprising applying gel-phase liposomes onto said one or more surfaces, wherein the temperature of said surface(s) at the time of lubrication is below the phase transition temperature Tof said liposomes. The method can be used for lubricating non-biological surfaces, and also for lubricating the surfaces of a biological tissue in a mammalian subject, e.g., for treating joint dysfunction.

Phosphatidylcholine lipid liposomes as boundary lubricants in aqueous media

A theranostic composition and method for determining the cell-specific potency of drugs is provided. Further, compositions and methods useful for studying the therapeutic profile of one or more drugs within a cell microenvironment, including but not limited to a tumor, are provided.

Compositions and methods for therapeutics prescreening

Pharmaceutical compositions comprising at least one lipid-based particle encapsulating a proteolytic enzyme and a pharmaceutically acceptable carrier, wherein the proteolytic enzyme comprises at least 75% proteolytically active enzyme are provided. Methods of using same and producing same are also provided.

Collagenase loaded liposomes for enhancing drug delivery

The present disclosure is directed to methods and compositions for inhibiting a cancer cell using nucleic acid sequences encoding elephant p53 or elephant p53 amino acid sequences.

Methods and compositions for preventing or treating cancer

A method for using bodily fluids in determining the cell-specific potency of drugs is provided. A composition comprising a plurality of types of carriers, wherein each carrier comprises a single-cell lethal amount of a therapeutic agent and a unique barcode identifying that agent and wherein the composition comprises equal numbers of each carrier type, equal concentrations of the agent and equal concentrations of each barcode is also provided. Further, methods useful for studying the therapeutic profile of one or more drugs within a cell microenvironment, including but not limited to a tumor, are provided.

Methods for therapeutics prescreening in bodily fluids

A composition and method for the administration of therapeutic and/or diagnostic agents is provided. Specifically, a hybrid system, composed of polymer that harbors drug-loaded lipid nanoparticles, and use thereof for the administration of active agents e.g., anti-cancer agents, is provided.

Hybrid muco-adhesive delivery systems and use thereof

The present invention concerns methods of joint lubrication and/or prevention of cartilage wear making use of liposomes having membranes with at least one phospholipid (PL) of the group consisting of a glycerophospholipid (GPL) having two, being the same or different, C-Chydrocarbon chain and a sphingolipid (SPL) having a C-Chydrocarbon chain, the one or more membranes having a phase transition temperature in which solid ordered (SO) to liquid disordered (LD) phase transition occurs, the phase transition temperature being within a temperature of about 20&#xb0; C. to about 39&#xb0; C. for lubrication of joints.

Methods for joint lubrication and cartilage wear prevention making use of glycerophospholipids

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Binyamina, Israel

Avi Schroeder