Koninklijke Philips Corporation N.v.

Suprapolix B.v.

Xeltis B.v.

Aurelie Brizard

Dirk Jan Broer

Henricus Marie Janssen

Rudolf Mathias Johannes Nicolaas Lamariche

Serge Hendrikus Mathÿs Söntjens

Emial Pesters

Anton William Bosman

A method of using a fluorinated polymer having a glass transition temperature below 40 C as a contrast agent inF magnetic resonance imaging (MRI) of a solid object, said solid object comprising said contrast agent. The invention relates to a solid object comprising a structural component and an imaging component, wherein the imaging component is at least one fluorinated polymer. The invention relates to a method forF MRI in solid state using a contrast agent comprising a fluorinated polymer as well as a method for in vivo visualizing a scaffold. It further relates to a method for in vivo monitoring the degradation of a solid object in time, wherein the degradation is monitored in time by usingF MRI to visualize the solid object, and wherein the amount of degradation of the solid object is determined based on the decrease in the visibility of the amount ofF.

Use of a fluorinated polymer as a contrast agent in solid state 19F magnetic resonance imaging (MRI), scaffold comprising said polymer and use thereof

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Eindhoven, Netherlands

Aurelie Brizard