Gilead Sciences, Inc.

Institute of Organic Chemistry and Biochemistry Ascr, V.v.i.

Institute of Organic Chemistry and Biochemistry of the As Cr, V.v.i.

Aurelie Bourderioux

Michal Hocek

Petr Naus

The invention provides compounds of formula I, wherein R, Rand Rhave values defined in the specification and a pharmaceutically acceptable salt thereof; or an optical isomer thereof; or a mixture of optical isomers, as well as compositions comprising such compounds and therapeutic methods that utilize such compounds and/or compositions.

7-deazapurine nucleosides for therapeutic uses

The invention provides compounds of formula I: wherein R, Rand Rhave values defined in the specification and a pharmaceutically acceptable salt thereof; or an optical isomer thereof; or a mixture of optical isomers, as well as compositions comprising such compounds and therapeutic methods that utilize such compounds and/or compositions.

The invention provides compounds of formula I, wherein R1, R2 and R3 have values defined in the specification and a pharmaceutically acceptable salt thereof; or an optical isomer thereof; or a mixture of optical isomers, as well as compositions comprising such compounds and therapeutic methods that utilize such compounds and/or compositions.

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Etrechy, France

Aurelie Bourderioux