Biotie Therapies Corporation

Auni Juhakoski

Ferenc Fulop

David Smith

Marjo Pihlavisto

Zsolt Szakonyi

Laszlo Lazar

Lorand Kiss

Marta Palko

Istvan Szatmari

Ferenc Miklos

The invention relates to pyridazinone and pyridone compounds having formula (I) or (I'), and pharmaceutically acceptable salts, hydrates, and solvates thereof wherein R/Rand X and Xare as defined in the claims. The invention further relates to their use as inhibitors of copper-containing amine oxidases. The present invention also relates to the preparation of the aforementioned compounds and to pharmaceutical compositions comprising as an active ingredient(s) one or more of the aforementioned compounds, pharmaceutically acceptable salts, hydrates, or solvates thereof.

Pyridazinone and pyridone compounds

The invention relates to pyridazinone and pyridone compounds having formula (I) or (I'), and pharmaceutically acceptable salts, hydrates, and solvates thereof (I) wherein R/Rand X and Xare as defined in the claims. The invention further relates to their use as inhibitors of copper-containing amine oxidases. The present invention also relates to the preparation of the aforementioned compounds and to pharmaceutical compositions comprising as an active ingredient(s) one or more of the aforementioned compounds, pharmaceutically acceptable salts, hydrates, or solvates thereof. 

Pyridazinone compounds

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Raisio, Finland

Auni Juhakoski