Mycogen Corporation

Myocogen Corporation

August J Sick

Jewel M Payne

George E Schwab

Kenneth Edwin Narva

Mark Thompson

Luis Foncerrada

H Ernest Schnepf

Thomas E Gilroy

Gregory A Bradfisch

Frank H Gaertner

Leslie A Hickle

Kendrick Akira Uyeda

Novelgenes encoding toxins which are active against lepidopteran insects have been cloned from novel lepidopteran-activemicrobes. The DNA encoding thetoxins can be used to transform various prokaryotic and eukaryotic microbes to express thetoxins. These recombinant microbes can be used to control lepidopteran insects in various environments.

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Novelgenes encoding toxins which are active against lepidopteran insects have been cloned from novel lepidopteran-activemicrobes. The DNA encoding thetoxins can be used transform various prokaryotic and eukaryotic microbes to express thetoxins. These recombinant microbes can be used to control lepidopteran insects in various environments.

Novel genes encoding toxins which are active against lepidopteran insects have been cloned from novel lepidopteran-active microbes. The DNA encoding the toxins can be used to transform various prokaryotic and eukaryotic microbes to express the toxins. These recombinant microbes can be used to control lepidopteran insects in various environments.

Bacillus thuringiensis isolate active against lepidopteran pests, and genes encoding novel lepidopteran-active toxins

Bacillus thuringiensis isolated active against lepidopteran pests, and genes encoding novel lepidopteran-active toxins

Novel Bacillus thuringiensis genes encoding toxins which are active against lepidopteran insects have been cloned from novel lepidopteran-active B. thuringiensis microbes. The DNA encoding the B. thuringiensis toxins can be used to transform various prokaryotic and eukaryotic microbes to express the B. thuringiensis toxins. These recombinant microbes can be used to control lepidopteran insects in various environments.

Bacillus thuringiensis isolate active against lepidopteran pests, and

Disclosed and claimed are novel Bacillus thuringiensis isolates which have lepidopteran activity. Thus, these isolates, or mutants thereof, can be used to control such insect pests. Further, genes encoding novel .delta.-endotoxins can be removed from the isolates and transferred to other host microbes, or plants. Expression of the .delta.-endotoxins in such hosts results in the control of susceptible insect pests in the environment of such hosts.

Protein toxins active against lepidopteran pests

Bacillus thuringiensis isolate active against lepidopteran pests

A novel B.t. toxin gene toxic to lepidopteran insects has been cloned from a novel lepidopteran-active B. thuringiensis microbe. The DNA encoding the B.t. toxin can be used to transform various prokaryotic and eukaryotic microbes to express the B.t. toxin. These recombinant microbes can be used to control lepidopteran insects in various environments.

Bacillus thuringiensis isolate denoted B.t. PS81F, active against

The subject invention concerns a novel microbe and gene encoding a novel toxin protein with activity against insect pests of the order Coleoptera. Pests in the order Coleoptera do heavy damage to crops, e.g., corn. The novel Bacillus thuringiensis microbe of the invention is referred to as B.t. PS50C. The spores or crystals of this microbe, or mutants thereof, are useful to control coleopteran pests in various environments. The novel gene of the invention can be used to transform various hosts wherein the novel toxic protein can be expressed.

Coleopteran-active Bacillus thuringiensis toxin

This invention concerns novel gene probes which can be used to identify DNA from Bacillus thuringiensis microbes which encode protein endotoxins. The invention probes greatly facilitate the search for useful microbes hosting genes which encode toxins.

Probes for the identification of Bacillus thuringiensis endotoxin genes

Nematicidal .delta.-endotoxin encoding genes have been cloned from a novel Bacillus thuringiensis isolate known as B.t. PS17. These novel genes, designated B.t. PS17a, B.t. PS17b, B.t. PS17d, and B.t. PS17e, can be transferred to various microbial and plant hosts via known techniques. In the microbial or plant host, one or more of the genes of the invention can be used to express the novel nematicidal toxins to control susceptible nematodes.

PS176 gene encoding nematode-active toxin cloned from a bacillus

Bacillus thuringiensis isolates active against lepidopteran pests, and

Gene encoding a coleopteran-active toxin

A novel B.t. isolate with activity against lepidopteran insects is disclosed. This isolate is highly active against the beet armyworm. A gene from this isolate has been cloned. The DNA encoding the B.t. toxin can be used to transform various prokaryotic and eukaryotic microbes to express the B.t. toxin. These recombinant microbes can be used to control lepidopteran insects in various environments.

Growing community of inventors

Oceanside, CA, United States of America

August J Sick