Basf Aktiengesellschaft

Badische Anilin- & Soda-fabrik Aktiengesellschaft

August Amann

Hubert Giertz

Rudolf Kropp

Franz Reicheneder

Albrecht Franke

Rolf Kretzschmar

Helmut Hagen

Josef Gries

Marco Thyes

Hans-Juergen Teschendorf

Horst Koenig

Rainer Schlecker

Walter-Wielant Wiersdorff

Martin Traut

Gerhard Bolz

Johannes Kunze

Klaus Wilsmann

Heinz Georg Vilhuber

Dora I Reicheneder

Peter Thieme

Joerg Schuster

Novel 1-phenyl-4(1H)-pyridazinone-imines of the formula (I) ##STR1## which are substituted at the imine nitrogen, and their addition salts with a physiologically tolerated acid, processes for their preparation, pharmaceutical formulations containing these compounds, and their use as drugs, in particular as antidepressants, antiparkinson drugs and antihypotonic agents.

Novel pyridazinone-imines and their physiologically tolerated addition

Production of new 2-(o-alkylthiophenyl)-1,3-diazacycloalkene hydrohalides by reaction of a benzo-thietane-2-spiro-2'-(1',3'-diazacycloalkane) with an alkyl halide, and the new 2-(o-alkylthiophenyl)-1,3-diazacycloalkene hydrohalides which are pharmaceuticals, auxiliaries for the textile and rubber industries, plant protection agents and starting materials for the production of pharmaceuticals, plant protection agents and dyes.

Production of 2-(o-alkylthiophenyl)-1,3-diazocycloalkene hydrohalides

3-(P-Biphenylyl)-butyronitrile, its production and its use as an antiphlogistic agent.

3-(P-Biphenylyl)-butyronitrile and therapeutic compositions containing

New pyridazinium compounds which can be used as intermediates and are of interest because of their pharmacological properties, and their production.

Pyridazinium compounds and a process for their production

New anhydro-2-mercapto-1,3,4-thiadiazolium hydroxides substituted in the 4- and 5-position, their manufacture and their use as medicaments.

Anhydro-2-mercapto-1,3,4-thiadiazolium hydroxides

New pyridazinium compounds which can be used as intermediates and are of interest because of their pharmacological properties, and their production. The invention relates to new pyridazinium compounds and their production. These compounds are of pharmacological interest. In DOS No. 1,912,941 6-alkoxypyridazinium compounds are said to have valuable pharmacological properties. Furthermore pyridazinium compounds are known for example as starting materials for pesticides and dyes from DOS No. 2,003,461 or U.S. Patent 3,510,488. The quaternization of pyridazines into pyridazinium compounds is described in an article in Acta. Chem. Scand., 21 (1967), 1067 to 1080, and the reaction of 6-chloropyridazinium compounds with amines is described in volume 23 (1969), 2534 to 2536.

4-Amino pyridazinium compounds having pharmacalogical properties

Cardiac stimulants and vasopressor agents for peroral and parenteral administration containing 6-alkoxy-pyridazinium compounds as active ingredients.

Sympathicomimetic remedy inducing vasopressor effects after oral and

Carbamates derived from polycyclic .gamma.-hydroxylactones and their production. The compounds may be used as pharmaceuticals by virtue of their analgesic properties.

Growing community of inventors

Ludwigshafen, Germany

August Amann