University of Houston System

Endomagnetics Limited

The University of Texas System

University College London

Audrius Brazdeikis

Simon Richard Hattersley

Peter Georg Laitenberger

Morteza Naghavi

Ching-Wu Chu

Quentin Andrew Pankhurst

Jaroslaw Wosik

Subhasis Sarangi

Paul Cherukuri

A probe and method for detecting magnetic particles. In one embodiment, the probe includes a probe core having a first end and a second end, the probe core defining two regions for containing coils of wire, one of the regions being adjacent the first end of the cylindrical probe core; two sense coils, one each of the sense coils being located in a respective one of the regions; and two drive coils, one each of the drive coils being located in a respective one of the regions, wherein the regions are separated by a distance equal to or greater than the diameter of one of the coils and a source of a secondary magnetic drive field. In another embodiment, the frequency of the drive signal of the secondary magnetic drive field is less than the frequency of the drive signal of the primary drive coils.

Magnetic detector

A probe for detecting magnetic particles. In one embodiment, the probe includes: a cylindrical probe core having a first end and a second end, the cylindrical probe core defining two channels for containing coils of wire, one of the channels being adjacent the first end of the cylindrical probe core; two sense coils, one each of the sense coils being located in a respective one of the channels; and two drive coils, one each of the drive coils being co-located with the respective sense coil in a respective one of the channels.

A well-posed magnetic imaging method is disclosed that exploits the non-linear behavior of the characteristic time scale of the N&#xe9;el relaxation for obtaining accurate high-spatial resolution images of magnetic tracers. The method includes placing an object in a selection field (static field) generated by three pairs of orthogonally arranged coil (drive coils), supplying prudently choice currents to the drive coils, a zero field voxel (ZFV) is formed that can be positioned anywhere in the local region of interest (ROI), switching the magnetizing field off, and collecting an image.

Imaging method for obtaining spatial distribution of nanoparticles in the body

An intraluminal sensor designs for multifunctional characterization of injured, stunned, infarcted myocardium, atherosclerotic plagues and tumors are disclosed. Various embodiments of the present invention comprise the sensor tips for a catheter. The tips comprises differential sensor arrangements, and use built-in electromagnet assemblies for a single or multiple axis sensing of various parameters of local magnetic field.

Intraluminal multifunctional sensor system and method of use

A system () including a catheter mounted magneto sensor (), such as a superconducting quantum interference device (SQUID), and methods using the system are disclosed, where the system and method are designed to detect changes in a magnetic field in a body of interest, such as a patient, to detect changes in a magnetic field in a patient, to identify loci in a target body that accumulate magnetic particles or to identify vulnerable plague in a patient.

Intraluminal magneto sensor system and method of use

Apparatus for determining magnetic properties of materials comprises a portable probe (), an equipment trolley () holding cryogenics and electronics and connecting cables (). The probe () comprises a drive coil () and a correction coil (), the drive coil () being disposed symmetrically with respect to an inner second-order gradiometer sensor coil (). Electrical connectors in the form of 2-meter long Belden (1192A) microphone cables () are used to connect the apparatus on the equipment trolley () to the drive coil (), the correction coil () and the sensor coil (). The drive coil () is driven so as to generate a sinusoidally varying magnetic field. The electronics comprise a flux-locked loop (), a SQUID controller (), a data acquisition module (), which captures and processes the signals and a computer (). A liquid-nitrogen dewar () is supported on the equipment trolley () and houses a sensitive SQUID detector () and a transfer coil () made from copper. Possible applications of the apparatus include an intra-operative tool for sentinel lymph node detection in the treatment of breast cancer, and a non-destructive evaluation tool for detecting voids and defects in aluminum and applications in the aeronautics industry.

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Missouri City, TX, United States of America

Audrius Brazdeikis