Hisamitsu Pharmaceutical Company, Inc.

Toppan Printing Co., Ltd.

Atsushi Sonobe

Yasunori Takada

Takashi Yasukochi

Satoshi Amano

Koji Sakairi

Tomohiro Shinoda

Atsushi Matsushima

Akio Takeuchi

Motohiro Suzuki

Kenji Atarashi

Shinichi Yokota

In a patch comprising a support layer and an adhesive agent layer, the adhesive agent layer comprises free asenapine, a maleic acid alkali salt, and a rubber-based adhesive agent.

Patch

A support film for a tape material, includes a film-shaped support formed of polyurethane; and a barrier layer containing an aromatic isocyanate-based polyurethane and a layered inorganic compound and formed on one surface of the support.

Support film for tape material, and tape material

The present invention provides a patch comprising a backing and an adhesive layer laminated on one side of the backing, wherein the adhesive layer comprises asenapine or a pharmaceutically acceptable salt thereof, an adhesive base and a low molecular weight amine.

Asenapine-containing patch

A patch comprises a backing and an adhesive layer laminated on at least one surface of the backing, in which the adhesive layer contains at least one selected from the group consisting of fentanyl and salts thereof, and contains an adhesive base material and an antioxidant having a sulfur atom in its molecule.

The present invention provides a compound represented by the formula (I) or a pharmaceutically acceptable salt thereof: wherein R is a hydrogen atom, a Calkyl group optionally substituted with one or more hydroxyl groups, a Calkoxy group, or a cyano group.

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Tsukuba, Japan

Atsushi Sonobe