Sony Corporation

Chugai Seiyaku Kabushiki Kaisha

Sony Semiconductor Solutions Corporation

Atsushi Muto

Tomoyuki Igawa

Takehisa Kitazawa

Tsukasa Suzuki

Tsutomu Nakajima

Tetsuo Kojima

Zenjiro Sampei

Tetsuhiro Soeda

Chifumi Imai

Kazutaka Yoshihashi

Yukiko Nishida

Tomohiro Takahashi

Atsumi Niwa

Yoshiyuki Akiyama

Takashi Miyamoto

Shinichirou Etou

Kenichi Shigenami

Tomonori Yamashita

Takayuki Sekihara

Takayuki Kai

Natsuhiro Aota

Masafumi Yamashita

Solid state imaging devices and electronic devices are disclosed. In one example, an imaging device includes photoelectric conversion sections arranged on a first chip and at least a part of each of detection circuits, an arbiter, and a signal processing circuit arranged on a second chip stacked on the first chip. A first region in the first chip in which the photoelectric conversion sections is arrayed and a second region in the second chip in which at least a part of each of the detection circuits is arrayed are at least partially superimposed in a stacking direction, and a logic circuit including the arbiter and the signal processing circuit is arranged in a third region at least partially adjacent to the second region in the second chip.

Solid imaging device and electronic device

Imaging devices with increased numbers of parallel analog-digital converters with maintained chip size are disclosed. In one example, an imaging device has a stacked chip structure including semiconductor chips of first through third layers. A pixel array is formed on the semiconductor chip of the first layer. An analog circuit of an analog-digital converter is disposed on the semiconductor chip of the second or third layer. A digital circuit of the analog-digital converter is disposed on the other of the semiconductor chip of the second or third layer.

Imaging device and electronic apparatus

The present inventors attempted to produce antibodies that neutralize the activity of a substance having an activity of functionally substituting for FVIII to be used for the method of measuring the reactivity of FVIII in the presence of a substance having an activity of functionally substituting for FVIII. As a result, the inventors discovered that by using the produced antibodies, FVIII activity in the plasma of a hemophilia A patient can be evaluated accurately by one-stage clotting assay based on APTT, and also that FVIII inhibitor titer in the plasma of a hemophilia A patient carrying a FVIII inhibitor can be evaluated accurately by Bethesda assay based on APTT.

Antibody capable of neutralizing substance having activity alternative to function of coagulation factor VIII (FVIII)

Various bispecific antibodies that specifically bind to both blood coagulation factor IX/activated blood coagulation factor IX and blood coagulation factor X and functionally substitute for the cofactor function of blood coagulation factor VIII, that is, the function to promote activation of blood coagulation factor X by activated blood coagulation factor IX, were produced. From these antibodies, multispecific antigen-binding molecules having a high activity of functionally substituting for blood coagulation factor VIII were successfully discovered.

Methods of treatment that include the administration of bispecific antibodies

The present technology relates to an image sensor and an electronic apparatus which can make the image sensor a smaller without degrading performance of the image sensor. The image sensor includes a pixel array unit in which pixels including photoelectric conversion elements are arranged in a two dimensional manner, a row circuit configured to control row scanning of the pixel array unit, and a column processing unit configured to convert an analog signal read out from the pixel array unit into a digital signal. The pixel array unit is disposed on a first-layer substrate, and the row circuit and the column processing unit are disposed on different substrates which are underlying layers of the first-layer substrate and which are laminated on the first-layer substrate. The present technology is applicable to the image sensor.

Image sensor and electronic apparatus including multiple substrates

The present technology relates to a circuit substrate, an image sensor, and an electronic apparatus that are capable of suppressing generation of noise in a conductor loop, which is caused due to a change in the conductor loop. A circuit substrate according to the present technology includes a circuit that is formed of a conductor and is capable of forming a conductor loop, at least a part of the dimensions of the conductor loop being variable; and a plurality of conductors that are each formed at a position where an induced electromotive force is generated in the conductor loop by a magnetic field and each have a structure that suppresses a change in the induced electromotive force generated by a change in dimensions of the conductor loop, the magnetic field being generated by the plurality of conductors. The present technology is applicable to, for example, an image sensor and an electronic apparatus.

Circuit substrate, image sensor, and electronic apparatus

Bispecific antibodies

Growing community of inventors

Shizuoka, Japan

Atsushi Muto