Eisai Company, Limited

Eisai R&d Management Co., Ltd.

Atsumi Yamaguchi

Katsuji Nakamura

Tatsuo Watanabe

Yasuhiro Funahashi

Masayuki Matsukura

Akihiko Tsuruoka

Keiko Takahashi

Kazuki Miyazaki

Tomohiro Matsushima

Yuji Yamamoto

Hiroshi Obaishi

Junji Matsui

Toru Haneda

Yoshio Fukuda

Junichi Kamata

Ken-ichi Nomoto

Sachi Suzuki

Fusayo Mimura

Yasuyuki Suzuki

Yoshihiko Kotake

Jun Niijima

Takeshi Nagasu

Nozomu Koyanagi

Kentaro Yoshimatsu

Hiroshi Yoshino

Hiroyuki Sugumi

Toshimi Okada

Taro Semba

Toshimitsu Uenaka

Kyosuke Kito

Itaru Arimoto

Saori Miyano

Tadashi Kadowaki

Takako Yoshiba

Yusuke Adachi

Jun-ichi Kamata

Satoshi Goda

Kenji Matsui

Yusuke Narita

Hajime Shimizu

Ken-Ichi Nomoto

Kazuhiko Yamada

Kentaro Takahashi

Disclosed is a therapeutic agent for hepatocellular carcinoma, comprising 5-((2-(4-(2-hydroxyethyl)piperidin-4-yl)benzamide)pyridin-4-yl)oxy)-6-(2-methoxyethoxy)-N-methyl-1H-indole-1-carboxamide or a pharmacologically acceptable salt thereof.

Therapeutic agent for hepatocellular carcinoma

Compounds represented by the following general formula: [wherein Ais an optionally substituted 5- to 14-membered heterocyclic group, etc.; Xis &#x2014;O&#x2014;, &#x2014;S&#x2014;, etc.; Yis an optionally substituted Caryl group, an optionally substituted 5- to 14-membered heterocyclic group, etc.; and Tis a group represented by the following general formula: (wherein Eis a single bond or &#x2014;N(R)&#x2014;, Rand Reach independently represent a hydrogen atom, an optionally substituted Calkyl group, etc. and Zrepresents a Calkyl group, a Calicyclic hydrocarbon group, a Caryl group, etc.)], salts thereof or hydrates of the foregoing.

Nitrogen-containing aromatic derivatives

Compounds represented by the following general formula: [wherein Ais an optionally substituted 5- to 14-membered heterocyclic group, etc.; Xis &#x2014;O&#x2014;, &#x2014;S&#x2014;, etc.; Yis an optionally substituted Caryl group, an optionally substituted 5- to 14-membered heterocyclic group, etc.; and Tis a group represented by the following general formula: (wherein Eis a single bond or &#x2014;N(R)&#x2014;, Rand Reach independently represent a hydrogen atom, an optionally substituted Calkyl group, etc. and Zrepresents a Calkyl group, a Calicyclic hydrocarbon group, a Caryl group, etc.)],

Fused polycyclic heterocycle derivatives

Growing community of inventors

Tsukuba, Japan

Atsumi Yamaguchi