Osaka University

Ono Pharmaceutical Co., Ltd.

Terumo Kabushiki Kaisha

Nipro Corporation

Saraya Co., Ltd.

Atsuhiro Saito

Yoshiki Sawa

Shigeru Miyagawa

Yoshiki Sakai

Satsuki Fukushima

Takayuki Maruyama

Yoshihiko Hirata

Tadashi Sameshima

Kazuhisa Matsuda

Mizuyuki Ryu

Nanase Ishii

Motoki Tatsumi

Koichi Toda

Hirotatsu Ohkawara

Toru Kuratani

Asuka Nogami

Takayoshi Ueno

Yoshiki Watanabe

Fumiya Oohashi

Ryouhei Takeuchi

A cell cryopreservation method including adding a 1 volume % of a composition comprising 0.01 wt % to 20 wt % of a sophorose lipid to cells in a cell culture medium just before or up to 6 hours before cryopreserving the cells; and cryopreserving the cell culture medium, wherein the composition improves cell viability after cryopreservation compared to cells that are cryopreserved with a similar composition that does not contain the sophorose lipid.

Cell cryopreservation composition and cryopreservation method

The present invention provides a drug-eluting stent graft for preventing stent graft-related complications as well as treating aneurysm. Specifically, the present invention relates to a drug-eluting stent graft comprising a drug, a drug-retaining agent and a stent graft, and a method for therapy of aneurysm including the use of the drug-eluting stent graft.

Drug-eluting stent graft

A laminate of a sheet-shaped cell culture is disclosed, which has excellent operability and is suitable for implantation. A method is disclosed for producing a laminate of a fibrin gel and a sheet-shaped cell culture, including a step of dripping a liquid containing fibrinogen onto an upper surface of a sheet-shaped cell culture, a step of spraying a liquid containing thrombin onto the surface, and a step of forming a fibrin gel layer on the surface by a reaction between fibrinogen and thrombin; and a laminate of a fibrin gel and a sheet-shaped cell culture produced by the method are disclosed.

Method for producing laminate of sheet-shaped cell culture and fibrin gel

Provided is an advanced heart failure treatment material, as a myocardial/cardiovascular regeneration device, that self-assembles, which can improve the universality and be used in an emergency by commercialization with no need of cell-culturing (cell-free) by controlling stem cells, and has a high therapeutic effect on the fundamental treatment of intractable cardiovascular diseases, in particular, advanced heart failure, in which not only the saving of lives but also improving the patient's quality of life (QOL) are urgent issues. The advanced heart failure treatment material includes a pharmaceutical agent, an agent holding for the pharmaceutical agent, and a myocardial support device.

Advanced heart failure treatment material as myocardial/cardiovascular regeneration device

Growing community of inventors

Suita, Japan

Atsuhiro Saito