Warner-lambert Company

Atma Chaudhari

Pauline H Pan

Frank A Volpe

Heinrich P Scheurer

Joseph K Lee

A pleasant-tasting, substantially alcohol-free oral mouthwash composition is effective in eliminating the bacteria and other oral microflora responsible for the production of plaque, periodontitis, gingivitis, gum disease and bad breath. The composition consists of a unique blend of the essential oils thymol or eucalyptol, methyl salicylate, menthol and tripartite blend of peppermint flavor oils that are dissolved in solution using a non-ionic surfactant blend.

Alcohol free mouthwash

The invention provides a dissolution cell and method for determining the in-vitro release rate of a drug in suitable form, e.g. a suppository. The cell includes a solid rectangular top wall and a pair of trapezoidal side walls extending from the top wall. Disposed between the side walls are a pair of end walls and a bottom wall each comprised of a wire mesh material. The bottom wall and end walls can be made in one piece. The top wall has an opening and a flanged extension which can be coupled to a suitable rotating device. In use the cell containing the drug is rotated in a suitable dissolution medium and the rate of release of the drug is determined by analyzing the amount of drug released to the dissolution medium at predetermined intervals.

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Scarborough, Canada

Atma Chaudhari