One Drop Biosensor Technologies, LLC

Sano Intelligence, Inc.

One Health Biosensing Inc.

Informed Data Systems Inc.

Ashwin Pushpala

Matthew Chapman

Alan Szmodis

Scott Wallace Miller

Hooman Hafezi

Weldon Hall

Dominic M Pitera

Michael Gifford

Pil Ho Chung

Steven Portela

Mark Prommel

Abhijit Ghosh

Mark D Prommel

Dominic Pitera

A system and method for monitoring body chemistry of a user, the system comprising: a housing supporting: a microsensor comprising a first and second working electrode, a reference electrode, and a counter electrode, and configured to access interstitial fluid of the user, and an electronics subsystem comprising a signal conditioning module that receives a signal stream, from the microsensor, wherein the electronics subsystem is configured to detect an impedance signal derived from two of the first working electrode, the second working electrode, the reference electrode, and the counter electrode; and a processing subsystem comprising: a first module configured to generate an analysis indicative of an analyte parameter of the user and derived from the signal stream and the impedance signal, and a second module configured to transmit information derived from the analysis to the user, thereby facilitating monitoring of body chemistry of the user.

Biomonitoring systems and methods of loading and releasing the same

Charging station

Applicator assembly

System for monitoring body chemistry

Sensor assembly

A microsensor and method of manufacture for a microsensor, comprising an array of filaments, wherein each filament of the array of filaments comprises a substrate and a conductive layer coupled to the substrate and configured to facilitate analyte detection. Each filament of the array of filaments can further comprise an insulating layer configured to isolate regions defined by the conductive layer for analyte detection, a sensing layer coupled to the conductive layer, configured to enable transduction, and a selective coating coupled to the sensing layer, configured to facilitate detection of specific target analytes/ions. The microsensor facilitates detection of at least one analyte present in a body fluid of a user interfacing with the microsensor.

On-body microsensor for biomonitoring

A microsensor and method of manufacture for a microsensor, comprising an array of filaments, wherein each filament of the array of filaments comprises a substrate and a conductive layer coupled to the substrate and configured to facilitate analyte detection. Each filament of the array of filaments can further comprise an insulating layer configured to isolate regions defined by the conductive layer for analyte detection, a sensing layer coupled to the conductive layer, configured to enable transduction of an ionic concentration to an electronic voltage, and a selective coating coupled to the sensing layer, configured to facilitate detection of specific target analytes/ions. The microsensor facilitates detection of at least one analyte present in a body fluid of a user interfacing with the microsensor.

Method of manufacturing multi-analyte microsensor with microneedles

Biomonitoring systems and methods of loading and releasing the same are disclosed herein. In one embodiment, a biomonitoring system includes a wearable sensor patch and an applicator. The sensor patch has a filament and an electronics subsystem. The sensor patch is configured to detect a parameter of an analyte in fluid of a user when it is adhered to the user's skin and the filament extends into the user's tissue. The applicator includes first and second applicator portions and a spring positioned within an interior of the second application portion between the first and second applicator portions. When the applicator transitions from a loaded mode to a released mode, the spring transitions from a first state of compression to a second, lower state of compression and accelerates the first applicator portion and the wearable sensor patch toward the user's skin such that the filament extends into the user's tissue.

Wearable microneedle patch

Growing community of inventors

San Francisco, CA, United States of America

Ashwin Pushpala