Melinta Therapeutics, Inc.

Bioversys Ag

Rib-x Pharmaceuticals, Inc.

P2 Science, Inc.

Other

Ashoke Bhattacharjee

Erin M Duffy

Zoltan F Kanyo

Rongliang Lou

Joseph A Ippolito

Jay J Farmer

Deping Wang

Shili Chen

Adegboyega K Oyelere

Joel A Goldberg

Yusheng Wu

Joseph M Salvino

Yi C Chen

Dane M Springer

Hardwin O'Dowd

Brian T Wimberly

Jiacheng Zhou

Jennifer N Tran

Roger Hanselmann

Alia Orbin

Marco DeVivo

Joyce A Sutcliffe

Edward C Sherer

Yanming Du

Andrea Marra

Patrick Foley

Sandra Sinishtaj

Yuanqing Tang

Matthew H Scheideman

Timothy S McConnell

John N Abelson

Yi Heng Chen

Yonghua Yang

Yong Tu

Tania Salam

Jacek G Martinow

Ik-Hyeon Paik

Marco Devivo

Matthew Alan Garcia

Trudy Grossman

Somenath Chowdhury

Vinay Thakur

Wan Lau

Yi Chen

Jacek G Martynow

Matthew Scheideman

The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals. In some embodiments, the present disclosure provides a compound of Formula (A):

Substituted pyrrolo[2,3-d]pyrimidines as antimicrobials

The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals. In some embodiments, the present disclosure provides a compound of Formula (I):

Antimicrobial compounds and methods of making and using the same

The present disclosure relates to methods of treating, preventing, reducing the risk of, or delaying the onset of microbial infections in humans and animals that are caused by or involves one or more microorganisms which are capable of being used as biological weapons, the method including administering a pyrrolocytosine compound or a tautomer thereof or a pharmaceutically acceptable salt of the compound or tautomer.

Biodefense agents

The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals. In some embodiments, the present disclosure provides a compound of Formula (I) or tautomer thereof or a pharmaceutically acceptable salt of the compound or tautomer

Antimicrobials methods of making and using the same

The present disclosure pertains to new methods of performing a hydrodealkenylation of monounsaturated alcohols, thiols, and derivatives thereof, such as terpenes and derivatives, comprising ozonolysis and quenching using a sulfinic acid or sulfinic acid salt.

Methods for hydrodealkenylation

The invention relates to cosmetic compositions comprising certain polyethers, polyether derivatives (e.g., polymeric alcohols and derivatives thereof), and methods of making and using the same, specifically in the field of cosmetic or personal care compositions applied to the skin or the hair.

Cosmetic compositions comprising polyether polymers

The invention relates to vicinal diol ether derivatives of certain polyether polymers, compositions comprising the same, and methods of making the same via reaction with substituted or unsubstituted epoxides, and methods of using the same.

Vicinal diol ether derivatives of polyether polymers

The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals. In some embodiments, the present disclosure provides a compound of Formula (I) or tautomer thereof or a pharmaceutically acceptable salt of the compound or tautomer. 

Antimicrobials and methods of making and using same

The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals.

The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals. In some embodiments, the present disclosure provides a compound of Formula (I): or a tautomer thereof or a pharmaceutically acceptable salt of the compound or tautomer. 

The present invention relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals.

The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals. In some embodiments, the present disclosure provides a compound of Formula (I) or a tautomer thereof or a pharmaceutically acceptable salt of the compound or tautomer. 

The present invention relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, and/or reducing the risk of microbial infections in humans and animals.

Methods and compounds for treating, preventing, reducing the risk of and/or delaying the onset of a microbial infection in a subject are disclosed herein, wherein the microbial infection is caused by one or more microorganisms (e.g., one or more bacteria) which can be used as a biological weapon, such as, and. Also disclosed are pharmaceutical compositions or kits for treating, preventing, reducing the risk of and/or delaying the onset of a microbial infection.

Growing community of inventors

Cheshire, CT, United States of America

Ashoke Bhattacharjee