Tris Pharma, Inc.

Tulex Pharmaceuticals Inc.

Ashok Perumal

Yu-Hsing Tu

Kalyan Kathala

Ketan Mehta

Romona Bhattacharya

Yingjun Fan

Alivia Chaudhuri

Provided herein are desmopressin oral liquid formulations. Also provided herein are methods of making and using desmopressin oral liquid compositions for the treatment of certain diseases including diabetes insipidus, enuresis, hemophilia A, von willebrand disease, high blood urea levels and others.

Desmopressin oral compositions

Compositions are provided for the liquid oral administration of topiramate and its salts. The invention further provides methods for treating diseases and disorders using the compositions.

Compositions and methods for treating epilepsy, seizures and other conditions

An oral methylphenidate extended release tablet is described, which can be scored and still retain its extended release profile. The tablet contains a combination of an uncoated methylphenidate-ion exchange resin complex, a barrier coated methylphenidate-ion exchange resin complex-matrix, and an uncomplexed methylphenidate active component. Following administration of a single dose of the extended release methylphenidate chewable tablet, a therapeutically effective amount of methylphenidate is reached in less than about 20 minutes and the composition provides a twelve-hour extended release profile.

Methylphenidate extended release chewable tablet

An oral methylphenidate extended release tablet is described, which can be scored and still retain its extended release profile. The tablet contains a combination of an uncoated methylphenidate&#x2014;ion exchange resin complex, a barrier coated methylphenidate&#x2014;ion exchange resin complex&#x2014;matrix, and an uncomplexed methylphenidate active component. Following administration of a single dose of the extended release methylphenidate chewable tablet, a therapeutically effective amount of methylphenidate is reached in less than about 20 minutes and the composition provides a twelve-hour extended release profile.

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Monmouth Junction, NJ, United States of America

Ashok Perumal