Advanced Cardiovascular Systems, Inc.

Abbott Cardiovascular Systems, Inc.

Ashok A Shah

Eugene T Michal

Syed F A Hossainy

Stephen D Pacetti

Ni Ding

Wouter Erik Roorda

Syed F Hossainy

Yung-Ming Chen

Thierry Glauser

Yiwen Tang

Charles David Claude

Santosh V Prabhu

James K Hong

Srinivasan Sridharan

Irina Astafieva

Connie S Kwok

John Whatley

Rahul Bhagat

Daryush Mirzaee

Evgenia Mandrusov

Vinayak Bhat

Judy A Guruwaiya

Deborra Sanders Millare

K T Venkateswara Rao

Deborra Sanders-Millare

Kt Venkateswara Rao

A coating for an implantable device such as a stent is provided including micronized peptides. A method of making the same is also provided.

Methods of forming a micronized peptide coated stent

The present application teaches a coating having a biologically compatible compound conjugated to, or blended with, a polymer, wherein the polymer includes at least one olefin-derived unit and at least one unit derived from a vinyl alcohol, an allyl alcohol, or derivatives thereof.

Coatings for implantable medical devices

A segmented polyurethane and an amphiphilic random or block copolymer are disclosed. The segmented polyurethane and the amphiphilic random or block copolymer can be used for fabricating a coating for an implantable medical device such as a stent.

Coatings for implantable medical devices comprising hydrophilic substances and methods for fabricating the same

Micronized peptide coated stent

Polymer coatings for medical devices are disclosed. The polymers can include at least one unit derived from ethylene and at least one vinyl unit or acrylic unit. The coatings can have a biologically compatible compound conjugated to, or blended with, the polymer.

A hybrid stent is formed which exhibits both high flexibility and high radial strength. The expandable hybrid stent for implantation in a body lumen, such as a coronary artery, consists of radially expandable cylindrical rings generally aligned on a common longitudinal axis and interconnected by one or more links. In one embodiment, a dip-coated covered stent is formed by encapsulating cylindrical rings within a polymer material. In other embodiments, at least some of the rings and links are formed of a polymer material which provides longitudinal and flexural flexibility to the stent. These polymer rings and links are alternated with metallic rings and links in various configurations to attain sufficient column strength along with the requisite flexibility in holding open the target site within the body lumen. Alternatively, a laminated, linkless hybrid stent is formed by encapsulating cylindrical rings within a polymer tube.

Hybrid intravascular stent

A coating for a medical device, particularly for a drug eluting stent, is described. The coating can include a polyacrylate, a blend of polyacrylates, or a blend of the polyacrylate with other polymers, for example, poly(ethylene-co-vinyl alcohol).

Polyacrylates coatings for implantable medical devices

Coatings for implantable medical devices and methods for fabricating the same are disclosed. The coatings include carboxylated acrylates and polycationic peptides, for example R7.

Coatings for implantable medical device containing polycationic peptides

A composition comprising an ethylene vinyl alcohol copolymer and a dimethyl acetamide solvent is provided for forming a coating on prostheses such as stents. The composition can include an active agent or therapeutic substance. Methods are also provided for coating the stents.

Ethylene vinyl alcohol-dimethyl acetamide composition and a method of coating a stent

An ethylene vinyl alcohol coating for an implantable device or prosthesis, such as a stent, is provided. Compositions are also provided for coating the implantable device. The compositions can include an ethylene vinyl alcohol copolymer added to an iso-propyl alcohol (IPA)/water solvent. Active agents, such as actinomycin D, can be included in the composition to be carried by the copolymer matrix.

Ethylene vinyl alcohol composition and coating

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San Jose, CA, United States of America

Ashok A Shah