Mammoth Biosciences, Inc.

Ashley Tehranchi

Lucas Benjamin Harrington

Xin Miao

Pedro Patrick Draper Galarza

Janice Sha Chen

James Paul Broughton

Jasmeet Singh

Andrew Besancon Lane

Maria-Nefeli Tsaloglou

Clare Louise Fasching

Described herein are devices, systems, fluidic devices, kits, and methods for detection of target nucleic acids associated with diseases, cancers, genetic disorders, a genotype, a phenotype, or ancestral origin. The devices, systems, fluidic devices, kits, and methods may comprise reagents of a guide nucleic acid targeting a target nucleic acid, a programmable nuclease, and a single stranded detector nucleic acid with a detection moiety. The target nucleic acid of interest may be indicative of a disease, and the disease may be communicable diseases, or of a cancer or genetic disorder. The target nucleic acid of interest may be indicative of a genotype, a phenotype, or ancestral origin.

Programmable nuclease compositions and methods of use thereof

Growing community of inventors

San Francisco, CA, United States of America

Ashley Tehranchi