Asuragen, Inc.

Interpace Diagnostics Corporation

Ashish Choudhary

Sylvie Beaudenon-Huibregtse

David Allen Brown

Gary J Latham

Sachin Sah

Alex Adai

Stephanie Volz

Elizabeth Mambo

Tiffany Sanford

The present invention concerns methods and compositions for identifying a miRNA profile for a particular condition, such as thyroid nodules or thyroid cancer, and using the profile in the diagnosis of a patient for a condition, such as thyroid nodules or thyroid cancer.

miRNAs as biomarkers for distinguishing benign from malignant thyroid neoplasms

Disclosed herein are methods for the automated reconstruction of a genotype of a gene, fragment, or genomic region using exhaustive enumeration. The methods can be used to reconstruct the genotype of any GC-rich sequence, such as the CGG repeat region in the 5' UTR of FMR1 or the CCG repeat region in the 5&#x2032; UTR of FMR2. Also disclosed is an apparatus for use in conducting automated genotype reconstruction, as well as methods of diagnosis and treatment using exhaustive enumeration methods to reconstruct and identify genotypes associated with a disease or disorder.

Comprehensive FMR1 genotyping

This application describes miRNAs that may be used as serum or plasma biomarkers for characterizing lung disease in a patient. These miRNA biomarkers may be used alone or in combination with other markers for the diagnosis, prognosis, or monitoring of diseases such as lung cancer.

MiRNA biomarkers of lung disease

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Austin, TX, United States of America

Ashish Choudhary