Pentax Corporation

Hoya Corporation

Katakura Chikkarin Co., Ltd.

Asako Matsushima

Masanori Nakasu

Tsuyoshi Ishikawa

Masahiro Kohketsu

Takahiro Fukuhara

Kazuyoshi Yamaguchi

Kaoru Arai

Makoto Otsuka

A method for manufacturing a sintered compact having high density, and a sintered compact manufactured by the manufacturing method are provided. The manufacturing method comprises the steps of preparing hydroxyapatite powder, molding a green compact, shaping the green compact, and sintering the green compact. Further, a method for manufacturing a sintered compact having high light permeability, and a sintered compact manufactured by the manufacturing method are provided. The manufacturing method comprises the steps of preparing hydroxyapatite powder, molding a green compact, shaping the green compact, primary sintering, and secondary sintering. Furthermore, a cell culture base formed from the sintered compact described above is provided, by which affinity of various cells with bone can be properly determined. Moreover, a cell culture base by which affinity of various cells with bone can be properly determined is provided. The cell culture base is mainly composed of a calcium phosphate based compound, and is highly compacted.

Method for manufacturing a sintered compact for use as a cell culture base

A prosthetic filler for a living body having excellent storage properties and handlability is disclosed. The prosthetic filler includes calcium phosphate granules and porous small chips made of an organic material for binding these calcium phosphate granules to each other. The prosthetic filler is made by mixing the calcium phosphate granules and the small chips of the organic material. When the prosthetic filler is used for a living body, it is added with water, and then they are kneaded to become a paste state. Thus obtained paste state prosthetic filler is injected into a bone defect site or the like to restore it.

Prosthetic filler for a living body and method of manufacturing the prosthetic filler

A method of manufacturing a ceramic composite comprises the steps of preparing at least two ceramics bodies to be bonded together, each of the at least two ceramics bodies having a bonding surface; preparing a slurry in which primary particles of a bonding ceramic are dispersed; applying the slurry to the bonding surface of at least one of the ceramic bodies to be bonded; and sintering the ceramic bodies between which the slurry has been interposed to bond them. In this method, the bonding ceramic in the slurry is preferably constituted from the same ceramic starting material as that of the at least one of the ceramic bodies to be bonded. In this way, it becomes possible to manufacture, with a simple technique, a ceramic composite having a required strength and excellent biocompatibility and biosafety.

Ceramic composite and manufacturing method thereof

A sustained release drug carrier comprises a ceramic composite which is formed by bonding a plurality of ceramic bodies together, and drugs impregnated into the ceramic composite. A method of manufacturing the sustained release drug carrier comprises the steps of: (i) preparing ceramic bodies to be bonded together, each of the ceramic bodies having a bonding surface; (ii) preparing a slurry in which primary particles of a bonding ceramics are dispersed; (iii) applying the slurry to the bonding surface of at least one of the ceramic bodies to be bonded; (iv) sintering the ceramic bodies between which the slurry has been interposed to bond them together, to obtain a ceramic composite; and (v) impregnating a drug into the obtained ceramic composite. According to the structure and method described above, it is possible to provide a sustained release drug carrier whose drug release properties can be controlled and which is capable of exhibiting better drug release action suitable for the application sites, type of drugs to be carried, and the like.

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Saitama, Japan

Asako Matsushima