Pfizer Corporation

Asako Ishibashi

Kiyoshi Kawamura

Mikio Morita

Tomoki Kato

Sachiko Mihara

This invention relates to compounds of the formula (I): or pharmaceutically acceptable salts thereof, wherein: R, R, R, A and m are each as described herein and compositions containing such compounds and the use of such compounds in the treatment of a condition mediated by 5-HTagonistic activity such as, but not limited to, gastroesophageal reflux disease, gastrointestinal disease, gastric motility disorder, non-ulcer dyspepsia, functional dyspepsia, irritable bowel syndrome (IBS), constipation, dyspepsia, esophagitis, gastroesophageral disease, nausea, central nervous system disease, Alzheimer's disease, cognitive disorder, emesis, migraine, neurological disease, pain, cardiovascular disorders, cardiac failure, heart arrhythmia, diabetes and apnea syndrome.

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Chita-gun, Japan

Asako Ishibashi