Z Square Ltd.

Bar-ilan University

Universitat De Valéncia

Asaf Shahmoon

Zeev Zalevsky

Javier Garcia

Yevgeny Beiderman

Nisim Nisan Ozana

Israel Margalit

Vicente Mico

Amihai Meiri

Nadav Arbel

Oran Herman

Martin Sanz Sabater

Yael Bishitz

Alex Zlotnik

David Zigdon

Omer Itzchak Wagner

Sigal Kremer-Tal

Hamutal Slovin

Itzchak Omer Wagner

A system for producing a multicore optical fiber includes a source of electromagnetic radiation in a spectral range that is suitable for inducing photopolymerization of a transparent polymer. An arrangement of one or more optical components is configured to concurrently focus the radiation that is emitted by the source on a plurality of elongated regions of the transparent polymer so as to photopolymerize the transparent polymer solely in the elongated regions to increase the index of refraction of the elongated regions such that in the optical fiber that is formed of the transparent polymer after the elongated regions are photopolymerized, each of the elongated regions functions as a core of the optical fiber and regions of the transparent polymer that surround the elongated regions function as a cladding of each of the cores.

Optical fiber from a single polymer

Multicore fibers and endoscope configurations are provided, along with corresponding production and usage methods. Various configurations include an adiabatically tapered proximal fiber tip and/or proximal optical elements for improving the interface between the multicore fiber and the sensor, photonic crystal fiber configurations which reduce the attenuation along the fiber, image processing methods and jointed rigid links configurations for the endoscope which reduce attenuation while maintaining required flexibility and optical fidelity. Various configurations include spectral multiplexing approaches, which increase the information content of the radiation delivered through the fibers and endoscope, and configurations which improve image quality, enhance the field of view, provide longitudinal information. Various configurations include fiber-based wave-front sensors. Many of the disclosed configurations increase the imaging resolution and enable integration of additional modes of operation while maintain the endoscope very thin, such as spectral imaging and three dimensional imaging.

Enhancing imaging by multicore fiber endoscopes

A system for imaging may include an illumination system that includes a light source to generate a light beam; and a spatial encoding pattern generator comprising one or a plurality of optical elements to encode the imaging beam so as to concurrently illuminate an object by a plurality of different spatial encoding patterns, wherein each encoding pattern of said different encoding patterns is characterized by a distinct wavelength of the imaging pattern. The system may also include an imaging sensor for receiving the encoded imaging beam transmitted through the object or reflected off the object; and a processor for decoding image data from the imaging and reconstructing an image of the object.

Spatial encoding system decoding system imaging system and methods thereof

Endoscopes, multicore endoscope fibers and configuration and operation methods are provided. The fibers may have hundreds or thousands of cores and possibly incorporate working channel(s) and additional fibers. The fiber may be used at different optical configurations to capture images of tissue and objects at the distal tip and to enhance a wide range of optical characteristics of the images such as resolution, field of view, depth of field, wavelength ranges etc. Near-field imaging as well as far-field imaging may be implemented in the endoscopes and the respective optical features may be utilized to optimize imaging. Optical elements may be used at the distal fiber tip, or the distal fiber tip may be lens-less. Diagnostics and optical treatment feedback loops may be implemented and illumination may be adapted to yield full color images, depth estimation, enhanced field of views and/or depths of field, and additional diagnostic data.

Illumination sources for multicore fiber endoscopes

A system and method monitoring conditions of a subject's body including a control unit receiving image data and data indicative of an external stimulation applied to the body during collection of the image data therefrom, a memory utility, and a processor utility. The image data is indicative of a sequence of speckle patterns generated by the body according to a certain sampling time pattern. The processor utility performs processing the image data utilizing the data indicative of the applied external field(s), including determining a spatial correlation function between successive speckle patterns in the sequence, and determining a time varying spatial correlation function in the form of a time-varying function of a feature of the correlation function indicative of a change of the speckle pattern over time; selecting a parameter of the time-varying spatial correlation function, and applying a model to the parameter to determine a corresponding body condition; and generating output data indicative of the corresponding body condition.

Method and system for non-invasively monitoring biological or biochemical parameters of individual

Multicore fiber endoscopes

Growing community of inventors

Petah-Tikva, Israel

Asaf Shahmoon