Bristol-Myers Squibb Compnay

Arvind Mathur

Ashvinikumar V Gavai

James Aaron Balog

Michael J Orwat

Philip Michael Sher

William N Washburn

Gregory S Bisacchi

Sreekantha Ratna Kumar

Ashok Vinayak Purandare

Emily Charlotte Cherney

Todd J Friends

Kumar Balashanmuga Pabbisetty

Zheming Ruan

Michael C Myers

Kathleen M Poss

Scott A Shaw

Lan-Ying Qin

Amarendra B Mikkilineni

Benjamin P Vokits

Samuel J Bonacorsi, Jr

Jianqing Li

Durga Buchi Raju Barre

K Selva Kumar

Shun Su

Adam James Clarke

Ravindar N Girotra

Donald JP Pinto

Ii Leon M Smith

Hima Kiran Potturi

Disclosed are compounds of Formula (I): or stereoisomers, tautomers, or salts thereof, wherein each R is independently H or D. Also disclosed are methods of using such compounds to decrease the levels of IKZF1-4 proteins; and pharmaceutical compositions comprising the compound. The compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.

Substituted phenyl oxazolone compounds

The present invention provides process useful for the preparation of intermediates which are useful in the preparation of amino acids useful in preparing peptide receptor modulators, for example agonists or partial agonists of such peptide receptors. Such peptide receptor modulators include, for example glucagon like peptide-1 receptor modulators which are useful for the amelioration of the diabetic condition.

Process for the preparation of amino acids useful in the preparation of peptide receptor modulators

Compounds of the formula ##STR1## or pharmaceutically acceptable salts thereof wherein: A is a bond, --(CH.sub.2).sub.n -- or --CH(B)--, where n is an integer of 1 to 3 and B is --CN, --CON(R.sup.9)R.sup.9' or --CO.sub.2 R.sup.7 ;

Catecholamine surrogates useful as .beta..sub.3 agonists

Compounds of the formula ##STR1## and pharmaceutically acceptable salts thereof wherein: A is a bond or --OCH.sub.2 --, where the oxygen is linked to R.sup.1 ;

Sulfonic, phosphonic or phosphiniic acid .beta..sub.3 agonist derivatives

Growing community of inventors

Bridgewater, NJ, United States of America

Arvind Mathur