Leland Stanford Junior University

Sanofi

Arutselvan Natarajan

Sanjiv Sam Gambhir

Parag Mallick

Christian Lange

Jochen Kruip

Ingo Focken

Benjamin Joseph Hackel

Richard H Kimura

Mathias Gebauer

Edwin Chang

Susanta K Sarkar

Ohad Ilovich

Lingyun Xu

Nick Hughes

Carsten H Nielsen

The invention relates to a companion diagnostic antibody-like binding protein based on the humanized monoclonal antibody, DS6, to be used as diagnostic tool for in vivo detection and quantification of the tumor-associated MUC1-sialoglycotope, CA6.

Immuno imaging agent for use with antibody-drug conjugate therapy

The present disclosure provides methods of treating cancer and modifying a cancer treatment for a cancer with an anti-EGFR drug by creating PRDX6 expression profiles and using the profiles to evaluate and optionally modify treatment. The present disclosure also provides assays and systems for assessing sensitivity of a cancer to an anti-EGFR therapy.

Methods of treating cancer sensitive to anti-EGFR therapy and modifying treatment using peroxiredoxin 6 biomarker

Embodiments of the present disclosure provide for labeled probes such as aCu-FN3 probe (FN3 refers to fibronectin type 3 domain); methods of making labeled probes; pharmaceutical compositions including labeled probes; methods of using labeled probes; methods of diagnosing, localizing, monitoring, and/or assessing non-Hodgkin's lymphoma, cancers, tumors, precancerous cells, and related biological events using labeled probes; kits for diagnosing, localizing, monitoring, and/or assessing non-Hodgkin's lymphoma, cancers, tumors, precancerous cells, and related biological events; and the like.

Probes and methods of imaging non-Hodgkins lymphoma

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Sunnyvale, CA, United States of America

Arutselvan Natarajan