Council of Scientific and Industrial Research

Arutla Viswanath

Ahmed Kamal

Earla Vijaya Bharathi

Gadupudi Ramakrishna

Jayanti Naga Srirama Chandra Murty

Jonnala Surendranadha Reddy

Dudekula Dastagiri

Farheen Sulthana

Kamal Ahmed

Inshad Ali Khan

Nitin Pal Kalia

Yellamelli Valli Venkata Srikanth

Ponnampalli Swapna

Gorre Balakishan

Farheen Sultana

Erla Vijaya Bharathi

Paidakula Raju

Ayinampudi Venkata Subba Rao

The present invention provides nitrofurfuryl substituted phenyl linked piperidino-oxadiazolone compounds of general formula (A) as anti-tubercular agents; wherein G=formula (B); X&#x2550;H, F; R&#x2550;H, CH, CH, Benzyl. 

Nitrofurfuryl substituted phenyl linked piperidino-oxadiazoline conjugates as anti-tubercular agents and process for the preparation thereof

The present invention provides a compound of general formulae 3a-i to 6a-i, 7a-i to 10a-i, 12a-i to 15a-i, 16a-i to 19a-i, 21a-i to 24a-i, 25a-i to 28a-i, 30a-i to 33a-i, 34a-i to 37a-i and 39a-i to 42a-i, 43a-i to 46a-i useful as potential antitumour agents against human cancer cell lines and a process for the preparation thereof. 

Isoxazole/isoxazoline/combretastatin linked dihydroquinazolinone hybrids as potential anticancer agents and process for the preparation thereof

The present invention provides a compound of general formula A, useful as potential anticancer agents against eleven human cancer cell lines. The present invention further provides a process for the preparation of diaryl ether linked pyrrolo[2,1-c][1,4]benzodi azepine conjugates attached through different alkane spacers of general formula A. 

Diaryl ether linked pyrrolo [2,1-c][1,4] benzodiazepine hybrids and process for the preparation thereof

The present invention provides a compound of general formula A, useful as potential antitumour agents against five human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]naphthodiazepine linked substituted piperazine conjugates attached through different alkane spacers of general formula A. (Formula I) General formula A. Where R=R'=(Formula II). n=1-9 and R&#x2033;=methyl, ethyl, acetyl, benzyl, piperinoyl, 4-fluorophenyl, 4-chlorophenyl, 4-methoxyphenyl, pyridyl, pyrimidyl. 

Pyrrolo[2,1-c][1,4]naphthodiazepine linked piperazine compounds and a process for the preparation thereof

The present invention provides a compound of general formulae 5a-r, 9a-i to 13a-i and 17a-i to 22a-i, useful as potential antitumour agents against human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]benzodiazepine hybrids of general formulae 5a-r, 9a-i to 13a-i and 17a-i to 22a-i. 

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The present invention provides 3-arylethynyl substituted quinazolinone compounds of formula (A) as potential anticancer agents against sixty human cancer cell lines. R&#x2550;H, OH, OCH; R&#x2550;H, OH, CH, OCH, NO; R&#x2550;H, OH, OCH, F, Cl; R+R=&#x2014;OCHO&#x2014;; R&#x2550;H, OH, CH, OCH; R&#x2550;H, OH, CH, OCH; R&#x2550;H, OCH. 

3-arylethynyl substituted quinazolinone compounds

The present invention provides a compound of general formula 7, useful as potential antitumour agents against five human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]benzodiazepine linked imidazo[1,5-a]pyridine conjugates attached through a piperazine moiety and different alkane spacers of general formula 7 

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Hyderabad Telangana, India

Arutla Viswanath