Dr. Reddy's Laboratories, Incorporated

Upsher Smith Laboratories, Inc.

Acrotech Biopharma Inc.

Tonix Medicines, Inc.

Arun Jana

Sreekanth Manikonda

Rajesh Gandhi

Sameer Shrinivas Kunte

Nagaprasad Vishnubhotla

Ashish Anvekar

The present invention provides a high-dose oral pharmaceutical composition and high drug loading of isotretinoin with low fill-weight, and smaller size capsules, and methods of preparation and use thereof.

Pharmaceutical compositions comprising isotretinoin and processes for preparation and uses thereof

The invention provides a pharmaceutical composition for intranasal administration comprising a salt of sumatriptan or a physiologically acceptable solvate thereof, an alkyl glycoside or saccharide alkyl ester and optionally at least one pharmaceutically acceptable excipient, wherein the said composition provides Tvalue of less than 30 minutes upon said administration. Other aspects and embodiments are contemplated and described. The invention also provides a pharmaceutical composition for intranasal administration comprising a triptan, a pharmaceutically acceptable vehicle and a mucosal permeation enhancer, wherein upon said administration said composition provides a Tsubstantially equivalent to subcutaneous administration of said triptan. Other aspects and embodiments are contemplated and described.

Formulations comprising triptan compounds

Growing community of inventors

Panna, India

Arun Jana