Gilead Calistoga LLC

Arthur Yeung

Jennifer Anne Treiberg

Jerry B Evarts

Musong Kim

Leena Patel

Stephane Perreault

Lafe J Purvis, Ii

Lafe J Purvis

Lafe J Ii Purvis

The present disclosure provides phosphatidylinositol 3-kinase (PI3K) inhibitors of formula (I), or pharmaceutically acceptable salts thereof, in which R, R, n, R, R, Rand Rare as defined herein. These compounds are useful for treatment of conditions mediated by one or more PI3K isoforms, such as PI3K&#x3b4;. The present disclosure further provides pharmaceutical compositions that include a compound of formula (I), or pharmaceutically acceptable salts thereof, and methods of using these compounds and compositions to treat conditions mediated by one or more PI3K isoforms, such as PI3K&#x3b4;.

Phosphatidylinositol 3-kinase inhibitors

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Redmond, WA, United States of America

Arthur Yeung