The Binding Site Group Limited

Other

Gambro Lundia Ab

Arthur Randell Bradwell

Markus Storr

Hermann Goehl

Robert A Smith

Dan Simmons

Graham Mead

The application provides a rodent or possum trap () comprising: a tunnel () for receiving a rodent or possum, a mechanical kill mechanism (), the kill mechanism comprising, a spring-loaded strike edge () and optionally additionally comprises a mechanical trigger, and at least one trap door () having a closed position and an open position; wherein when the kill mechanism () is arranged so that when it is activated by a rodent in the tunnel () it kills the rodent and opens the trap door () to release the deceased rodent from the rodent trap.

Trap

A method of making antibodies to a selected part P of an immunoglobulin molecule ZP, Z comprising the non-selected part of ZP, P being the selected part of ZP which comprises a hidden epitope of the light chain, said method comprises tolerizing the source of antibodies, by administering to the source a compound containing the non-selected part Z or a part of Z and administering antibodies to the non-selected part Z or a part of Z; wherein these administered antibodies are specific to an Fc region of ZP;

Production of antibodies and to medical uses involving antibodies

There is provided a method of reducing blood free light chain concentration in a subject, the method comprising the step of subjecting the subject's blood to haemodialysis, haemodiafiltration or haemofiltration. There is also provided the use of a dialysis membrane which is a membrane that allows passage of molecules having a molecular weight of up to 45 kDa in presence of whole blood, and has a molecular weight exclusion limit in water of about 200 kDa in the preparation of a haemodialysis unit for conducting haemodialysis, haemodiafiltration or haemofiltration on a subject to reduce blood free light chain concentration in the patient.

Method of removing antibody free light chains from blood

Radial immunodiffusion and like techniques

Growing community of inventors

Birmingham, United Kingdom

Arthur Randell Bradwell