The Purdue Frederick Company

Arthur McFadden

Bola V Shetty

Peter Hofer

Analgesic and anti-inflamatory compounds of the formula ##STR1## wherein n=0-1,

1-substituted, 2,3-diphenyl-3-hydroxymethyl pyrrolidines, where the 2-

Analgesic and anti-inflammatory compounds are provided. These compounds possess the following general formula: ##STR1## wherein R=--COOR.sub.5, --CH.sub.2 CO.sub.2 H, ##STR2## wherein A and B=hydrogen, lower alkyl, hydroxy alkyl, lower alkyl amine, substituted lower alkyl amine, aminoalkyl, substituted aminoalkyl;

Analgesic and anti-inflammatory compounds

Analgesic 4-carboxy-pyrrolidin-2-one compound

The invention relates to compounds which exhibit diuretic and antihypertensive properties and have the following structures: ##STR1## or pharmaceutically acceptable salts thereof, wherein: X=halogen or trifluoromethyl

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East Brunswick, NJ, United States of America

Arthur McFadden