Medrad, Inc.

Bayer Healthcare LLC

Bayer Medical Care Inc.

Bayer Aktiengesellschaft

Bayer Intellectual Property Gmbh

Boston Scientific Corporation

Bridge Semiconductor Corporation

Other

International Business Machines Corporation

Bayer Healtcare LLC

Bayer Heatlhcare LLC

Arthur E Uber, Iii

Kevin P Cowan

Alan D Hirschman

David M Griffiths

Barry Tucker

Edward J Rhinehart

David M Reilly

Michael A Spohn

Mark Trocki

Frederick W Trombley, Iii

Rosemary Almon-Martin

Ralph H Schriver

James Albert Dedig

John Francis Kalafut

Eugene A Gelblum

Francis J Sciulli, Jr

Raymond C Hoffman

Michael J Swantner

Richard A Seman

Jaroslaw Wlodarczyk

Martin J Uram

Michael John Bonnette

Christopher David Capone

Eric Joel Thor

Gerald W Callan

John A Brosovich

David Arthur Berry

Gregory G Brucker

Michael Donald McDermott

Steven D Savage

Joseph B Havrilla

Barry Skirble

Robert Eric Uber

William Barone

Robert S Schwartz

Robert A Van Tassel

Chad Edward Bouton

John A Haury

Marlin S Heilman

Stephen R Schulte

Thomas P Joyce

Stephen E Weisel

Laszlo Trent Farago

Charles Marsh

Stephen Sams

Keith Lipford

Benjamin Thomas Krupp

Herbert M Grubic

Larry McCutchan

Jerry A Stokes

Michael A Riley

Karen M Zelenski

Walter Grumski

Marc A Mabie

Vera Pagano

David A Mishler

Thomas R Welch

Douglas Descalzi

Timothy Newing

Michael J Yanniello

Glen P Williams

James R Neill

Barry Iddon

William D Barlow

Russell Morrison Evans, Iii

Ronald Heller

Steven J Remis

Scott Griffith

Chelsea Marsh

Bruno Fazi, Jr

Jason L Bazala

Vince Delbrugge

Matthew Schrauder

Daniel Moore

Molly Bingaman

Barry Lynn McDaniel

Martin Rohrer

Sridhar R Balasubramanian

Roey Flor

Benjamin T Ewing

Scott A Bednar

Michael McDermott

Patrick Campbell

Dennis P Hack

Stanley R Lewandowski

Andreas Maihoefer

Edward P Liscio

Charles Lang

Martin J Gibler

Janel Petrilli

Seid W Waddell

Christopher Scutt

Vernon D Beck

Kent Diasabeygunawardena

Matthew J Leroch

Dave Berry

Emma Diasabeygunawardena

William J Jaecklein

Amy Chaya

Bernard J Hobi

A method and system determine, with a computer system including one or more processors, a plurality of parameters associated with a volume in an object over time in a series of sequence blocks. In a sequence block in the series of sequence blocks, the plurality of parameters are determined as occurring simultaneously in the volume in the object. At least one parameter of the plurality of parameters varies from the sequence block to another sequence block in the series of sequence blocks, and the plurality of parameters include a contrast related parameter associated with a concentration of a contrast agent in the volume in the object over time in the series of sequence blocks. The computer system generates a signal evolution based on the plurality of parameters of the volume in the object over time in the series of sequence blocks, the signal evolution defining the contrast related parameter over time in the series of sequence blocks.

Synthetic magnetic resonance imaging and magnetic resonance fingerprinting with a contrast agent, and determination of a contrast agent injection protocol

An assembly for retaining a pressure jacket () and a syringe () on a fluid injector, the assembly including a base plate () comprising a body (); at least a first retaining arm () and a second retaining arm () operatively mounted on the body of the base plate, the first retaining arm having a first retaining surface at a distal end thereof and the second retaining arm having a second retaining surface at a distal end thereof, wherein the first retaining surface and the second retaining surface are configured for abutting a distal surface of at least one of the pressure jacket and the syringe; a linkage assembly operatively connected to at least one of the first retaining arm and the second retaining arm, wherein the linkage assembly is configured to move at least one of the first retaining arm and the second retaining arm between at least a first open position and a closed position.

Pressure jackets and syringe retention features for angiography fluid injectors

A system, method, and computer program product for predicting, anticipating, and/or assessing tissue characteristics obtains measurement information associated with a parameter of a voxel of tissue of a patient measured at two or more time points, the two or more time points occurring before one or more characteristics of the voxel of the tissue are separable in an image generated based on the parameter of the voxel measured at a single time point of the two or more time points, and determines, based on the parameter of the voxel at the two or more time points, the one or more characteristics of the voxel of the tissue.

System, method, and computer program product for predicting, anticipating, and/or assessing tissue characteristics

A system and method for promoting and safeguarding the wellbeing of patients in relation to a fluid injection may obtain patient data; determine, based on the patient data, an initial risk prediction for a patient for a fluid injection to be administered to the patient, the initial risk prediction including a probability that the patient experiences at least one adverse event in response to the fluid injection; provide, to a user device, before the fluid injection is administered to the patient, the initial risk prediction; determine, after the fluid injection is started, sensor data associated with the patient; determine, based on the sensor data determined after the fluid injection is started, a current risk prediction including a probability that the patient experiences the at least one adverse event in response to the fluid injection; and provide, to the user device, the current risk prediction.

System, device and method for safeguarding the wellbeing of patients for fluid injection

A fluid injector system for delivering a multi-phase fluid injection to a patient and methods of fluid delivery is disclosed. Methods of creating and using a multi-aspect fluid path impedance model of the injector system are used. Modeling and adjustment of factors that affect impedance and prevent or reduce backflow, reduce the likelihood of fluid flow rate spikes and provide more accurate flow rates and mixing ratios of fluids may be repeated or happen essentially continuously during an injection. The adjustments may be determined before the injection or determined and/or adjusted during the injection. The determination may include sensor feedback commonly used in injectors such as pressure and position feedback as well as other sensors. In all cases, the user can be notified of adjustments through on-screen notices and/or through the recordation of the injection data by a control device of the injector at the conclusion of the injection.

Fluid path impedance assessment for improving fluid delivery performance

The present disclosure deals with the quickening of MRI examinations. Subjects of the present disclosure are a method, a system, a computer program product, a use, a contrast agent for use and a kit.

Forecast of MRI images by means of a forecast model trained by supervised learning

Provided is a method for delivering a medical fluid. The method includes delivering a fluid volume, which includes contrast and/or a flush fluid, at a preselected total volumetric flowrate during a first duration of a fluid delivery procedure. The amount of the contrast agent and the flush fluid in the fluid volume can be controllably varied during the first duration of the fluid delivery procedure so as to substantially maintain a preselected total volumetric flowrate throughout the first duration of the fluid delivery procedure. Also provided is a fluid delivery system capable of performing this method.

System and method for delivering a fluid with a consistent total volumetric flowrate

A method of maintaining an overall flow rate during a sequential delivery of at least two fluids to a patient's blood vessel includes delivering at least a first fluid into the patient's blood vessel at a first flow rate, delivering at least a second fluid into the patient's blood vessel at a second flow rate, and adjusting at least one of a first flow profile of the first flow rate and a second flow profile of the second flow rate to dampen a transient increase in the overall flow rate during a transition between delivering one of the first fluid and the second fluid to delivering the other of the first fluid and the second fluid.

System and method for improved fluid delivery in multi-fluid injector systems

Systems and methods for intelligently delivering fluid to a targeted tissue are described. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range. If the one or more sensed feedback parameters are not within the acceptable range, the systems and methods may include determining an adjusted velocity for the plunger necessary to adjust the pressure of the fluid in the pump so that the one or more sensed feedback parameters move within the acceptable range and directing the pump to distribute the fluid at the adjusted velocity.

Medical fluid injector

A diagnostic contrast composition includes a carrier fluid and a non-decaying gas-evolving fluid incorporated in the carrier fluid. The gas-evolving fluid has a vapor pressure sufficient to evolve the gas from a circulatory system within a lung of a patient. The gas-evolving fluid is a composition containing a sufficient quantity of atoms with an atomic number higher than 8 to provide an increased absorption sufficient to increase a Hounsfield Unit measurement in an image in a CT imaging system. The gas-evolving fluid is selected from the group consisting of xenon gas, krypton gas, sulfur hexafluoride, a perfluorocarbon, a brominated perfluorocarbon, and combinations thereof. The carrier fluid is selected from the group consisting of water, saline, saline comprising one or more blood proteins, and saline comprising dissolved lipids.

Contrast imaging agent with dissolved gas-evolving fluid

A syringe includes a barrel having a distal end, a proximal end, and a sidewall extending therebetween along a longitudinal axis. At least one engagement member protrudes from a terminal portion of the sidewall in a proximal direction along the longitudinal axis. The at least one engagement member tapers axially in a direction from the distal end toward the proximal end. The at least one engagement member is configured for engagement with a locking mechanism of a fluid injector to releasably lock the syringe with the fluid injector. A taper of the at least one engagement member is configured to rotationally guide the syringe into alignment with the locking mechanism and axially eject the syringe upon rotation of the syringe. The locking mechanism operatively engages the at least one engagement member regardless of an orientation of the syringe about the longitudinal axis relative to the injector.

Self-orienting syringe and syringe interface

A plunger for use with a syringe has a plunger body with a proximal end, a distal end, and a circumferential sidewall extending between the proximal end and the distal end along a plunger longitudinal axis. The plunger further has at least one resiliently deflectable retaining member having a first segment attached to the plunger body and a second segment protruding toward the distal end of the plunger body and deflectable relative to the first segment. The plunger further has at least one actuation member associated with the at least one resiliently deflectable retaining member. The at least one actuation member interacts with a piston to deflect the at least one resiliently deflectable retaining member upon rotation of the plunger relative to the piston. The plunger is engageable with the piston regardless of a rotational orientation of the piston relative to the plunger.

System and method for syringe plunger engagement with an injector

A medical injector including at least one syringe port for engaging at least one syringe and having a locking mechanism. The locking mechanism enables the syringe to self-align with the syringe port for locking engagement upon insertion of the syringe into the syringe port and to axially eject the syringe from the port upon rotational disengagement of the syringe from the port.

A pressure jacket for use with a fluid injector may have a pressure jacket body having a proximal end, a distal end, and a circumferential sidewall extending between the proximal end and the distal end along a pressure jacket longitudinal axis. The pressure jacket may further have at least one resiliently deflectable retaining member having a first segment attached to the pressure jacket body and a second segment protruding from the first segment toward the distal end of the pressure jacket body and deflectable relative to the first segment. The pressure jacket may further have at least one actuation member associated with the at least one resiliently deflectable retaining member. The at least one actuation member may interact with a housing of the fluid injector when the pressure jacket is connected to the housing to deflect the at least one resiliently deflectable retaining member upon rotation of the pressure jacket.

System and method for fluid engagement with a pressure jacket and syringe cap

Described is an in-scan phantom for use during an imaging procedure. The phantom can include at least one measuring insert and/or at least one measured insert. The measuring insert may have radiation detecting capabilities while the measured insert may include a radioactive material. Also described is an imaging modality system that includes an imaging modality and an in-scan phantom as well as methods of using the in-scan phantom for imaging a patient or performing a scout scan.

Quantification phantom for use with multiple imaging modalities

Growing community of inventors

Pittsburgh, PA, United States of America

Arthur E Uber, Iii