Other

A Enterprises, Inc.

Arthur Ashman

V Prasad Shastri

Leonard I Linkow

The present invention relates to a novel composition for dental, orthopedic and drug delivery purpose. Specifically, it relates to composition comprising an admixture of a resorbable bone substitute and a crosslinkable prepolymer. It also relates to the composition formed by crosslinking the admixture.

Crosslinkable polymeric materials and their applications

A soft tissue implant material is formed from biologically-compatible polymeric particles. The particles may have a diameter of up to about 500 microns and intraparticulate pores sized for ingrowth of soft tissue. The particles may have an inner core of a first biologically-compatible polymeric material and an outer layer generally surrounding the inner core, with the outer layer comprised of a second biologically-compatible polymeric material being hydrophilic and having a composition different from the composition of the first polymeric material. The material may be utilized with collagen or other matrix materials. This material may be used in a method of reforming soft tissues by implanting the material within soft body tissues to modify soft tissue defects such as wrinkles or oral gingival tissue defects and reshape soft tissue, e.g., for urinary bladder inconvenience.

Soft tissue substitute and method of soft tissue reformation

Biocompatible adhesive protective dressings, and methods of manufacturing and using the same, having properties suitable for use on moist tissues such as gingiva. The dressing may include a flexible sheet, e.g. a metal foil, with an irradiated gamma radiation sensitive adhesive on one surface. The properties of gamma sensitive adhesives are modified by exposure to gamma radiation so as to increase their adhesiveness and volume. The dressing may be applied to human or animal tissue to protect the tissue from the environment, and retain autogenous and other substances at the application site. The dressing may be used at surgical sites or wounds.

Biocompatible oral bandage, application and method of manufacture

A method for preserving the alveolar ridge surrounding a presently extracted root socket by backfilling the socket with bone graft material and installing an implant in the root socket area either immediately before backfilling or after backfilling and a delay in which new bone is allowed to grow into the bone graft material. In one embodiment, the dental implant is installed apically into the root socket immediately following root extraction. The open area of the root socket surrounding the implant is then backfilled with bone graft material immediately after implant placement. The implant is preferably a threaded implant (but it can be a cylinder-type) which is placed approximately three to six millimeters apically to said root socket. The bone graft material comprises synthetic bone alloplast such as Bioplant&reg; HTR&reg; and is hydrated using the patient's own blood obtained from the patient's bleeding extraction socket after penetration but prior to insertion of the bone graft material and the implant into said root socket. As an alternate embodiment, the presently extracted root socket is filled with bone graft material and primary or non-primary closure of the extraction site is performed. Bone-growth is promoted in the root socket by the bone graft material for 2-12 months. Then, after sufficient bone growth has been promoted, an implant is installed in the extraction site area in the normal manner.

Method and apparatus for performing ridge preservation and implant treatment

An improved assembly of a syringe and a nozzle tip for aspirating marrow blood from a surgical site and a method for using this improved syringe. The syringe includes a nozzle tip of special construction which has a sleeve portion, which fits on the free end of the barrel of the syringe, and a curved aspirating nozzle end. The nozzle tip includes a filter screen of preselected mesh size. A sufficient amount of marrow blood is aspirated through the curved aspirating nozzle end and the filter screen of the nozzle tip, thereby moving a preselected amount of marrow blood into the barrel of the syringe. The aspirated marrow blood then mixes with the granules of bone regeneration material disposed in the barrel of the syringe to form a viscous fluid mixture therein. The excess marrow blood, if any, is expelled through the curved aspirating nozzle end by applying a moderate manual pressure to the plunger of the syringe. After visual inspection of the formed viscous fluid mixture in the syringe, the nozzle tip is then manually removed from the syringe and the viscous fluid mixture is applied to a surgical site by applying manually pressure on the plunger of the syringe. The filter screen is mounted inside a flange adjoining the sleeve portion in the nozzle tip. This filter screen has openings of predetermined mesh size to prevent the granules of bone regeneration material from exiting through the nozzle tip during the aspirating of the marrow blood into the syringe barrel and prior to the removal of the nozzle from the syringe barrel and the expelling of the viscous mixture to a surgical site.

Combination syringe and aspirator for bone regeneration material and method for using the syringe

Biocompatible oral bandage, application and method of manufacuture

A submergible or non-submergible (&ldquo;one stage&rdquo;) screw-type implant for use in the immediate post-extraction site of a patient's tooth. In order to increase the ability of regenerated bone to anchor the implant, an upper portion of the implant has a preferably generally conical shape and has a plurality of spherical projections sintered to its outer surface to make it suitable for bone integration and retention. The lower portion of the implant has a cylindrical shape with threads extending over a portion thereof. A channel is located through the threads and is shaped so that one side forms a cutting edge that makes the lower portion of the implant self-tapping into the bone at the base of the tooth extension socket.

Immediate post-extraction implant

A method and apparatus for augmenting an endentulous alveolar ridge of a patient comprises the steps of (1) making a provisional denture-stent with a hollow space on the underside to account for the width, height and extent of the desired augmentation; (2) making an incision in, and reflecting, the gingiva where the augmentation is desired; (3) inserting bone graft material on the cortical plate; (4) suturing the gingiva; and (5) inserting the provisional stent over the bone graft material.

Method and apparatus for performing ridge augmentation

The present invention provides a kit system comprising a plurality of disposable kits, each kit being adapted for post-extraction dental implantation on a particular dental area. Each kit includes a dental implant of specified dimensions for a particular dental area of the mouth, a transfer coping attachable to the dental implant for creating an impression for making a model to produce a prosthetic tooth, bone graft material for filling the void area around a portion of the implant after implantation, burrs and bone expanders, and a portable housing for storing the dental implant, the transfer coping, the bone graft material, wound dressing and burrs and bone expanders. Each disposable kit includes indicia which uniquely identifies it with the particular dental area of use. The kit system may include a non-disposable instrument kit including a plurality of reusable and sterilizable tools such as insertion instruments, a scissor, and a suture holder, etc., for implementing post-extraction dental implantation, and a housing for storing the instruments. The invention further provides a method of using the kits.

Kit for immediate post-extraction implantation

A bone filter trap for harvesting autogenous bone and cell marrow and blood elements collected by an aspirator during medical and dental bone surgical procedures. The bone trap is disposed between the aspirator suction system and the aspirator tip. The bone filter or trap includes housing through which an air flow induced by the suction system is allowed to pass via inlet and outlet openings in the housing. A cylindrically-shaped mesh is longitudinally disposed therein. The cylindrically shaped mesh is open at its top end (facing the inlet opening) and is fitted with a removable solid base at the distal outlet end, such that the induced air flow carrying liquids, solids and gases from the patient surgical site is forced to pass through the mesh. The mesh is sized such that only autogenous bone and cell marrow and blood elements are trapped in the mesh. Upon completion of the medical procedure, the cylindrically-shaped mesh is removed from the inlet and outlet housings. A circularly-shaped plunger device is pushed up and down inside the mesh open end to effectively and efficiently dislodge the elements, (e.g., autogenous bone) trapped inside the cylindrically-shaped mesh and to compress it against the base. The base is removed from the mesh and the compressed autogenous bone mixture is pushed from within the mesh by the action of plunger. The resultant mixture can be utilized alone, or mixed with synthetic or other graft materials (e.g., alloplasts, allografts or xenografts).

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Westport, CT, United States of America

Arthur Ashman