Ivivi Health Sciences, LLC

Rio Grande Neurosciences, Inc.

Other

Endonovo Therapeutics, Inc.

Endonovo Technology, Inc.

Endonovo Therapetics, Inc.

Ivivi Technologies, Inc.

Arthur A Pilla

Iyer Viswanathan

Andre' A DiMino

Diana Casper

Berish Strauch

Andre′ A Dimino

Matthew Drummer

Andre′ DiMino

David John Muehsam

Charles Zablotsky

Ted Zablotsky

André A Dimino

Described herein are methods of treating neurological injury and conditions, in particular symptoms and complications arising from or caused by a stroke. These treatment methods can include the steps of generating a pulsed electromagnetic field from a pulsed electromagnetic field source and applying the pulsed electromagnetic field in proximity to a target region.

Apparatus and method for electromagnetic treatment of neurological injury or condition caused by a stroke

Embodiments of the invention include methods of treating a patient with physiological responses arising from an injury or condition, such as post-operative pain, traumatic brain injury, and cognitive defects. These treatment methods can include the steps of generating a pulsed electromagnetic field from a pulsed electromagnetic field source which is configured to simultaneously increase the rate of ion-dependent signaling, such as CaM/NO/cGMP signaling and to minimize the rate of inhibition of such signaling by natural compounds and applying the pulsed electromagnetic field in proximity to a target region affected by the injury or condition for a first treatment interval followed by an inter-treatment period with no electromagnetic field between treatment intervals to reduce a physiological response to the injury or condition.

Method and apparatus for electromagnetic treatment of living systems

Described herein are devices and methods for treating degenerative joint diseases with electromagnetic fields using one or more waveforms that are configured to modulate Cabinding to calmodulin and thereby modulate calmodulin-dependent nitric oxide signaling within joint and other affected tissue for the purpose of reducing pain and inflammation, as well as enhancing the healing and regeneration of such tissue.

Devices and method for treatment of degenerative joint diseases with electromagnetic fields

Apparatus and methods for delivering electromagnetic signals configured specifically to accelerate the asymmetrical kinetics of the binding of intracellular ions to their respective intracellular buffers, to enhance the biochemical signaling pathways plant animal and human molecules, cells, tissues, organs, portions of entire organisms and entire organisms employ for growth, repair and maintenance. Described herein are devices and methods that utilize repetitive bursts of waveforms configured to maximize the bound concentration of intracellular ions at their associated molecular buffers to enhance the biochemical signaling pathways living systems employ for growth, repair and maintenance. For example the systems and methods described herein may drive the binding of calcium to calmodulin (CaM), thereby enhancing the CaM-dependent nitric oxide (NO)/cyclic guanosine monophosphate (cGMP) signaling pathway.

Method and apparatus for electromagnetic enhancement of biochemical signaling pathways for therapeutics and prophylaxis in plants, animals and humans

Described herein are methods of treating neurological injury and conditions, in particular neurodegenerative conditions. These treatment methods can include the steps of generating a pulsed electromagnetic field from a pulsed electromagnetic field source and applying the pulsed electromagnetic field in proximity to a target region.

Apparatus and method for electromagnetic treatment of neurodegenerative conditions

Embodiments of the invention include methods of treating neurological injury and conditions, in particular, traumatic brain injury and physiological responses arising from injury or conditions. These treatment methods can include the steps of generating a pulsed electromagnetic field from a pulsed electromagnetic field source and applying the pulsed electromagnetic fieldin proximity to a target region affected by the neurological injury or condition to reduce a physiological response to the neurological injury or condition.

Method and apparatus for electromagnetic treatment of head, cerebral and neural injury in animals and humans

Described herein are methods of treating neurological injury and conditions, in particular neurological pain. These treatment methods can include the steps of generating a pulsed electromagnetic field from a pulsed electromagnetic field source and applying the pulsed electromagnetic field in proximity to a target region.

Apparatus and method for electromagnetic treatment of neurological pain

An apparatus and method for electromagnetic treatment of living tissues and cells comprising: configuring at least one waveform according to a mathematical model having at least one waveform parameter, said at least one waveform to be coupled to a angiogenesis and neovascularization target pathway structure; choosing a value of said at least one waveform parameter so that said at least waveform is configured to be detectable in said angiogenesis and neovascularization target pathway structure above background activity in said target pathway structure; generating an electromagnetic signal from said configured at least one waveform; and coupling said electromagnetic signal to said angiogenesis and neovascularization target pathway structure using a coupling device.

Electromagnetic treatment apparatus and method for angiogenesis modulation of living tissues and cells

Methods and devices for providing electromagnetic field treatment to a subject having a metal-containing implant or prosthesis at or near the treatment site. These treatment methods can include calibrating the treatment devices such that the treatment field provided is not distorted or affected by the presence of metal in the target location. Additionally, embodiments of the invention provide for wearable and adjustable electromagnetic treatment devices with reinforcing support members to maintain the structure of flexible metal applicators, which generate the therapeutic electromagnetic field.

Methods and devices for providing electromagnetic treatment in the presence of a metal-containing implant

Larmor Precession makes specific predictions about bound ion dynamics, based upon specific combinations of AC and DC magnetic fields. Especially significant is the fact that the external magnetic field environment determines the overall qualities of resonances or particular changes in bio-effects. Given a target with a particular gyromagnetic ratio, Larmor Precession makes predictions that are determined solely by a magnetic field environment itself. An embodiment according to the present invention comprises specific combinations of AC and DC magnetic fields configured to produce specific bio-effects. Preferably an embodiment according to the present invention comprises using Larmor Precession to develop Electromagnetic Field environments targeted towards enhancing or diminishing specific biological processes, including tumor growth, bone and tissue repair, and biological processes and using Larmor Precession to generate magnetic field conditions that take advantage of specific behaviors, including resonances conditions.

Electromagnetic field treatment apparatus and method for using same

An apparatus and method for electromagnetic treatment for treatment of molecules, cells, tissues, and organs comprising: configuring at least one waveform according to a mathematical model having at least one waveform parameter, said at least one waveform to be coupled to a target pathway structure; choosing a value of said at least one waveform parameter so that said at least waveform is configured to be detectable in said target pathway structure above background activity in said target pathway structure; generating an electromagnetic signal from said configured at least one waveform; and coupling said electromagnetic signal to said target pathway structure using a coupling device wherein said coupling device is an integral portion of a positioning device.

Integrated coil apparatus for therapeutically treating human and animal cells, tissues and organs with electromagnetic fields and method for using same

An apparatus and method for electromagnetic treatment of plants, animals, and humans comprising: configuring at least one waveform according to a mathematical model having at least one waveform parameter, said at least one waveform to be coupled to a target pathway structure; choosing a value of said at least one waveform parameter so that said at least waveform is configured to be detectable in said target pathway structure above background activity in said target pathway structure; generating an electromagnetic signal from said configured at least one waveform; and coupling said electromagnetic signal to said target pathway structure using a coupling device.

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Oakland, NJ, United States of America

Arthur A Pilla