Other

Genetic Laboratories, Inc.

Bioplasty, Inc.

Beisang, Arthur A.

Ersek, Robert A.

Beisang, Daniel J.

Beisang, Arthur A., Iii

Beisang Iii, Arthur A.

Arthur A Beisang

Robert A Ersek

Arthur A Beisang, Iii

Daniel G Holman

Daniel J Beisang

Arthur A Beisang Iii

Compositions of cross-linked polyvinylpyrrolidone (PVP) are disclosed that are generally in the form of an elastic, hydrophilic, water-insoluble viscous cohesive mass of material that has many important medical uses including uses as a filler for implants. The present invention also involves a process for producing such compositions.

Implant filling material and method

A receptacle for controlling and containing irrigation fluids administered to clean and irrigate a wound on a patient's body. The receptacle comprises a thin flexible film selected from the group consisting of polyethylene and polyvinyl chloride, and having an adhesive portion for sealing to the patient. The receptacle is in the form of a bag member and is utilized for retaining fluids along with a spraying or irrigation member, thereby enabling the wound irrigation procedure to be carried out in a closed system, and wherein upon completion of the procedure, the receptacle may be completely sealed and disposed of in an appropriate manner so as to avoid cross-contamination from a patient being treated to another person such as a health care professional or another patient.

Closeable, disposable wound care system

An improved micro-implantation method and composition for filling depressed scars, unsymmetrical orbital floors, muscle, lip, and other soft tissue defects is provided for use in reconstructive surgery procedures. Textured micro particles having an outside diameter between about 30 microns and 3000 microns are used with an appropriate physiologic vehicle cannula and syringe and/or pressure delivery system into a predetermined locus. The particles provide long-term filling of defects without migration loss.

Textured micro implants

Novel principles for treating urological and gastric fluid reflux disorders are disclosed wherein textured micro particles having a combination of average unidimensional particle size range and average particle texture which cooperate substantially to prevent loss of the micro particles from any injection site.

Treatment of urological and gastric fluid reflux disorders by injection

An improved bio-osmotic gel for filling implant lumens consisting substantially of an amount of a bio-compatible organic polymer and a solution of bio-compatible salt is disclosed which exhibits osmotic qualitites closely paralleling that of human body serum and improved radiolucency with respect to silicone oil and saline. The bio-osmotic gel can contain a polymer having the empirical formula [(CHCH.sub.2).sub.2 N(CH.sub.2).sub.3 CO].sub.n i.e. polyvinylpyrrollidone. The bio-compatible salt can be made of a low Z value salt such as sodium bicarbonate, sodium acetate, or sodium lactate. The gel material should have an osmolarity between 250 and 350 milliosmoles and have an X-ray absorption under standard exposure approximately equal to that of breast tissue such that processed mammographic X-ray film will have an optical density of 1.2 to 1.3 and an average penetrance of between 9.2 and 30.0 milliroentgens.

Bio-osmotic gel for implant prostheses

Capsular contracture causing firmness of soft silicone implants is a serious problem that may result from several causative factors that have as their final pathway, the development of increased scar tissue. The present invention has altered the formation of this scar encapsulation of silicone implants by texturing the silicone surface in order to gain fibroblast ingrowth into the interstices and thus prevent micromotion at the host prosthesis interface. It has been found that this produces a thinner fibrous capsule. Previously published work pertaining to animals and man has shown that similar texturing of tetrafluoroethylene (Teflon) and other substances achieves these goals. In accordance with work leading up to the present invention, textured silicone samples have been implanted in the subcutaneous layer of rabbits, the capsule formation and the host-prosthesis interface studied histologically. A difference between the smooth surface and the textured surface could be measured wherein the textured surface had a thinner capsule without contracture and the smooth surface had a thicker capsule with contraction.

Textured silicone implant prosthesis

An adhesive strip-like bandage for application to skin wounds for sealing the wound without surface stitches or staples. The wound closure strips may be fabricated from a bias cut, woven, or non-woven, polymer-based material or other film, exhibiting uni-directional stretch properties which permits the strips to stretch in a controlled manner during wound healing. The strip bandages are detachably mounted to a backing member and in one configuration comprise a comb-like structure.

Wound closure strips

A temperature control device containing a mixture of de-ionized water, propylene glycol, polysaccharides and plant gum for providing a moldable pillow-like surface for cooling/heating and positioning body organs or parts. A multi-layered container including an insulator, a radiant heat reflecting layer and a liquid impermeable outer layer permit autoclaving and provide directional cooling/heating. The inclusion of appropriate phase change chemicals or reciprocal ion-type chemicals or metal particles facilitate the stabilization of temperature over a predetermined temperature range.

Moldable cooling/heating device with directional cooling/heating

A process for treating animal tissue to make it acceptable for implantation in a human recipient without rejection or reabsorption, the process including the step of tanning the cartilage chemically or by irradiation: a preliminary dehydration step and a subsequent step of storage in an anti-microbial medium may also be used.

Preparation of animal tissues for surgical implantation in human

A photographic accessory, for application to a body surface and other medical and scientific uses, having dimensional graduations and color patches to facilitate correlation of photographic data with the actual size and color of the surface in question.

Photographic accessory

A method for preparing human and other animal unbilical cords for use as a vascular replacement and/or arterial venous fistula which permits the umbilical cord which is to be grafted to be preformed into a desired predetermined configuration. The method includes the steps of initially flushing the cord in an aqueous solution, and then mounting the flushed cord upon a mandrel having the desired configuration. The mounted cord is immersed in ethyl alcohol until substantially dehydrated and preformed, and is thereafter immersed for fixation in an aldehyde selected from the class consisting of dialdehyde starch and gluteraldehyde, with the aldehyde immersion fixing the tissue into a shape conforming to the mandrel upon which it is mounted.

Method of preforming vascular grafts of human and other animal origin

A method for preparing human and other animal umbilical cords for use as a vascular replacement and/or arterial venous fistula which permits the umbilical cord which is to be grafted to be preformed into a desired predetermined configuration. The method includes roughening the surface of the umbilical cord at the point of juncture with the host tissue, external to the umbilical cord, thereby improving the sealing arrangement at said juncture to allow for puncturing of the graft as well as mechanical retention. Additionally, the method may include the steps of flushing the cord in an aqueous solution either before or after roughening, and then the flushed cord is mounted upon a mandrel having the desired configuration. The roughened and mounted cord may then be immersed in ethyl alcohol until substantially dehydrated, and thereafter fixed in an aldehyde selected from the class consisting of dialdehyde starch and gluteraldehyde, with the aldehyde fixing the roughened tissue into a shape conforming to the mandrel upon which it is mounted.

Growing community of inventors

White Bear Lake, MN, United States of America

Arthur A Beisang