Duke University

Kuwait University

Artak Tovmasyan

Ines Batinic-Haberle

Ivan Spasojevic

Rima Abdul Ghani Ezzeddine

Anwar Gh A Gh Albanaw

Ludmil Tzvetanov Benov

James D Craik

Provided herein are fluoro-substituted porphyrin compounds, such as those having a structure represented by Formula (I), wherein Ris a C1-C8 alkyl that is substituted with at least 1 fluorine (e.g., a C1-C8 alkyl substituted with 1-17 fluorine atoms); and X is an anion (e.g. a halogen ion (e.g., chloride, etc.), PF, tosylate, besylate, and/or mesylate). Also provided herein are methods of making the fluoro-substituted porphyrin compounds, pharmaceutical formulations containing the same, and methods of use thereof.

Fluoro substituted porphyrin compounds, pharmaceutical compositions comprising the same, and methods of preparing and using the same

The method for fluorescent staining of cellular and intracellular membranes includes contacting a cell sample, such as a cell culture, with a fluorescent probe including Zn(II) meso-tetrakis(N-n-hexylpyridinium-4-yl)porphyrin tetrachloride (ZnTnHex-4-PyPCl). The fluorescent probe is an amphiphilic, water-soluble compound. The fluorescent probe does not interfere with cell culture media components or other staining products. The fluorescent probe is not harmful to cells.

Method for fluorescent staining of cellular and intracellular membranes

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Durham, NC, United States of America

Artak Tovmasyan