Izun Pharmaceuticals Corporation

Aron Jay Saffer

William Zev Levine

Zvi Gerald Loewy

Gabriel Nussbaum

Mina Fran

Mina Faran

The present invention provides therapeutic compositions comprising extracts of the plant speciesandand the extract(s) of at least one further plant selected from the group consisting ofand. The compositions of the invention are of particular utility in the management of inflammatory mucosal diseases of both viral and non-viral origin.

Herbal compositions for the treatment of mucosal lesions

Provided, among other things, is a method of treating or ameliorating an indication of non-mucosal topical tissue comprising periodically applying to such disease affected tissue a composition comprising: an effective amount of an appropriate composition of herbal bioactive comprising active(s) of one or more ofor, and an effective amount of a quaternary ammonium surfactant.

Topical anti-inflammatory combination

Provided, among other things, is a method of treating or ameliorating an indication of mucosal or adjacent tissue comprising periodically applying to mucosa at or adjacent to disease affected tissue a rinse comprising: an effective amount of appropriate composition of herbal bioactive comprising active(s) of one or more ofor; an antimicrobially effective amount of a quaternary ammonium surfactant; and optionally a polymer or mixture of polymers effective to coat said tissue and entrap said extract(s).

Mucosal formulation

Provided, among other things, is a slowly dissolvable film comprising: herbal bioactive agent(s); and polymer(s), dissolvable in the aggregate, wherein the film becomes adhesive as it is placed against a mucosal surface and begins to absorb moisture therefrom.

Anti-inflammatory dissolvable film

A method of treating or ameliorating an indication of mucosal or adjacent tissue comprising periodically applying to mucosa at or adjacent to disease affected tissue a rinse comprising: an effective amount of appropriate composition of herbal bioactive comprising active(s) of one or more ofor; an antimicrobially effective amount of a quaternary ammonium surfactant; and optionally a polymer or mixture of polymers effective to coat said tissue and entrap said extract(s).

Oral rinse

Provided, among other things, is a method of treating an indication of mucosal or adjacent tissue comprising periodically applying to mucosa at or adjacent to disease affected tissue a delivery device comprising a backing layer and an adhesive reservoir comprising an effective amount of appropriate composition of plant extract(s) comprising extract of, wherein the adhesive reservoir comprises 30 to 70 polymer by weight, of which a major portion comprises polyacrylic polymer, wherein the delivery device is flexible and tissue conforming.

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Bet Shemesh, Israel

Aron Jay Saffer