Baxter Travenol Laboratories, Inc.

Baxter International Inc.

Clintec Nutrition Company

Hyclone Laboratories, Inc.

Baker International Inc.

John Foley

Arnold Bilstad

Jeffrey E. Miripol

William R. Bratten

Dean Glash

Arnold C Bilstad

John T Foley

David V Bacehowski

Richard I Brown

Atif M Yardimci

David W Pennington

Sidney T Smith

Robert J Kruger

Paul Mario DiPerna

Scott R Ariagno

Mark E Williamson

Mark Perry

Alan W Marttila

T Michael Dennehey

Marc C Bellotti

Bradley H Buchanan

Michael R Prisco

Jeffrey E Miripol

Yves A Delmotte

Stephen B Kaufman

James S Slepicka

Dean M Glash

David L Amrani

William C Brown

James Diorio

Patrick N Huehls

Herbert M Cullis

Michael R Keilman

Michael F Wicnienski

Archie Woodworth

James W Yang

Cristina Stadler

Walker P Woodworth

Alan W Martilla

Martha C Pattillo

Robert Patterson

John Mark DeFoggi

Michael E Goodwin

Jeremy K Larsen

Whitt F Woods

Alice Marie Jandrisits

William R Bratten

Robert E Lewis

Thomas R Lillegard

David P Fisher

Robert L Gliniecki

Jerry W Newbrough

Bihong Wu

Edward G Oilschlager

Jerre T Kachmar

Robert L Petersen

Marianne M Boschelli

William L Schumacher

John Womelsdorf

Mark Kennedy

Joseph F Prybell

Wayne T Leblong

Jack Anthony

Ingrid McPhilliamy

John Mark Defoggi

A system for forming a fluid connection includes a first connector and a second connector. Both connectors include a tubular body having a membrane mounted on a distal end thereof. A support member facilitates the coupling of the connectors together so that the membranes are abutted together. Radiant energy is applied to the abutted membranes so as to first sterilize the membranes and then melt the membranes so that a passage is formed therethrough.

Sterile connector systems

The connection, assembly, or fill of two or more pre-sterilized components having at least one terminal end each for attachment to another component, and an apparatus for performing such a connection, while maintaining the sterility of the components is disclosed. The resulting connection is made permanent by bonding the contacting components together using either a solvent bonding technique, a radio frequency sealer, a heat sealer, or any other suitable process. The connection is preferably made within an active sterile field. Using a low-voltage electron beam instrument, such as the MIN-EB&#x2122;, a suitable sterile field sphere can be created. The terminal ends of the multiple components remain within the sterile field sphere until the possibility of contamination within the sealed components is significantly reduced to industry acceptable standards.

Method and apparatus for manipulating pre-sterilized components in an active sterile field

A reconstitution device is disclosed and includes a first container receiver having a first component cannula disposed therein, the first component cannula having a withdrawal port and a first transfer port formed thereon, a second container receiver having a second component cannula disposed thereon, the second component cannula having a vent port and a second transfer port formed thereon, a device body coupling the first container receiver to the second container receiver and having a transfer lumen formed therein, the transfer lumen in fluid communication with the first and second transfer ports, a selectively sealing interface secured to the device body and in fluid communication with the withdrawal port, and a venting member in communication with the vent port through a vent lumen.

Reconstitution device and method of use

This invention provides a medical device for delivering volumetric quantities of a first and a second biochemically reactive fluid in which separate MBUs atomize the fluids. The device of the present invention includes a fluid delivery device for laparoscopically delivering fluids having two feed conduits for delivering fluid to feed ports of the mechanical breakup units, the mechanical breakup units having two feed ports for receiving fluid from the feed conduits and directing such fluid into spin chambers and funneling portions having a sloped sidewall for directing fluid from the spin chambers through an exit port. The device is suitably dimensioned for creating a spray of two fluids with different viscosities such as fibrinogen and thrombin in such a manner that the thrombin spray cone encompasses the fibrinogen spray cone at a distance of about one inch from the exit port with a 0.5 cc/second flow rate to avoid depositing unreacted fibrinogen on a surface. Other instruments such as optical fibers may be incorporated within the device.

Mechanical breakup unit for biochemically reactive fluid delivery device

A vacuum demand valve for delivering a flowable material is disclosed. The valve has a housing having a proximal end, a distal end, an intermediate segment therebetween defining a passageway wherein the flowable substance can flow from the proximal end to the distal end. The housing can be a tubing. A valve member is located along the intermediate segment. The valve member has a closed condition wherein the flow of the flowable material from the proximal end to the distal end is stopped and an open condition wherein the flow of the flowable material from the proximal end to the distal end is unstopped. The valve member is biased in the closed condition and is responsive to a partial vacuum provided by the user through the passageway for placing the valve member in the open condition.

Vacuum demand valve

A vacuum demand value ( ) is capable of delivering a flowable material. The valve ( ) has a housing ( ) having a proximal end ( ), a distal end ( ), an intermediate segment ( ) therebetween defining a passageway ( ) wherein the flowable substance can flow from the proximal end ( ) to the distal end ( ). The housing ( ) can be tubing. A valve member ( ) is located along the intermediate segment ( ). The valve member ( ) has a closed condition wherein the flowable material from the proximal end ( ) to the distal end ( ) is stopped and an open condition wherein the flow of the flowable material from the proximal end ( ) to the distal end ( ) is unstopped. The valve member ( ) is biased in the closed condition and is responsive to a partial vacuum provided by the user through the passageway ( ) for placing the valve member ( ) in the open condition.

This invention provides a medical device for delivering volumetric quantities of a first and a second biochemically reactive fluid comprising a first container having an opening, the first container being adapted to contain the first biochemically reactive fluid; a second container having a second fluid opening adjacent the first fluid opening, the second container being adapted to contain the second biochemically reactive fluid; a spray unit for separately atomizing the first and second biochemically reactive fluids into an aerosol with at least one energy source of a liquid energy, a mechanical energy, a vibration energy, and an electric energy; a fluid pressurizer for pressurizing the first and the second biochemically reactive fluids for delivery under pressure through the spray unit onto a surface; and wherein the first and second biochemically reactive fluids first mix on the surface.

Fibrin delivery device and method for forming fibrin on a surface

A device is provided for reconstituting a lyophilized or powdered medicament such as blood factor VIII which must be reconstituted just prior to use, such as by introduction of a sterile fluid from a syringe, which comprises a housing having an upper section capable of receiving a syringe and a lower section capable of receiving a vial containing the medicament in co-axial alignment with the syringe, a middle section connecting the upper and lower sections which has a central aperture which forms a passageway for fluid transfer between the syringe and the vial, and a hollow vented spike which extends downwardly from the central aperture for a length sufficient to ensure that the lower end of the spike will pierce the seal and enter the interior of a vial housed in the lower section of the device. The invention is advantageous because the vented opening in the spike will allow for an equalization of the pressure after the piercing of the vial by the spike which will facilitate the use of the device. In addition, the device also features an ergonomic design which maximizes the safety and efficiency of the reconstitution of important medicaments such as blood factors, and allows for easily manipulation of the device by patients such as those with Factor VIII deficiency who may suffer from related physical ailments which limit their dexterity.

Device for reconstituting medicaments for injection

Growing community of inventors

Deerfield, IL, United States of America

Arnold C Bilstad