Idorsia Pharmaceuticals Ltd

Arne Von Bonin

Claney Lebev Pereira

Bopanna Monnanda

Marilda Lisboa

Sharavathi Guddehalli Parameswarappa

Sylvia Oestreich

Jessica Przygodda

Madhu Emmadi

Daniel Knopp

Arun Naini

The present invention relates to a synthetic saccharide of general formulate (I) that is related toPS-II cell-surface polysaccharide and conjugate thereof. Said synthetic saccharide, said conjugate and pharmaceutical composition containing said synthetic saccharide or said conjugate are useful for prevention and/or treatment of diseases associated with. Furthermore, the synthetic saccharide of general formula (I) is useful as marker in immunological assays for detection of antibodies againstbacteria.

Stable vaccine against

The present invention relates to a synthetic saccharide of general formula (I) that is related toserotype O1, O2, O2ac, and O8 O-polysaccharide and carbapenem-resistantST258 O-polysaccharide and conjugate thereof. Said synthetic saccharide, said conjugate and pharmaceutical composition containing said synthetic saccharide or said conjugate are useful for prevention and/or treatment of diseases associated with. Furthermore, the synthetic saccharide of general formula (I) is useful as marker in immunological assays for detection of antibodies againstbacteria.

Vaccine against klebsiella pneumoniae

The present invention relates to a synthetic oligosaccharide of general formula (I): T*-[(—U—U—U—U—U)—(V—V—V)-T-O-L-E that is related toserotype O3, O3and/or O5 lipopolysaccharide and conjugate thereof. Said synthetic oligosaccharide, said conjugate and pharmaceutical composition containing said synthetic oligosaccharide or said conjugate are useful for prevention and/or treatment of diseases associated with. Furthermore, the synthetic oligosaccharide of general formula (I) is useful as marker in immunological assays for detection of antibodies againstserotype O3, O3and/or O5 bacteria.

Vaccine against

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Basel, Switzerland

Arne Von Bonin