Centogene Ag

Centogene Gmbh

Roche Diagnostics Gmbh

Biotecon Diagnostics Gmbh

Centogene IP Gmbh

Arndt Rolfs

Hermann Mascher

Matthias Beller

Alexander Gasch

Freimut Wilborn

Anahit Pews-Davtyan

Jan Lukas

Moritz Frech

Christian Junghanss

Eckart Fleck

Cornelia Berghof

Kornelia Berghof

Claudia Cozma

Vera Regitz-Zagrosek

Anja Braeuer

Cordt Groenewald

Peter-Nicholas Robinson

Christian Eisenloeffel

Bj&ouml;rn Heidrich

Frank Tiecke

Peter Bauer

Charles Mason-Brown

The present invention is related to a method for diagnosing Niemann-Pick disease in a subject comprising

Method for the diagnosis of Niemann-Pick disease

The present invention is related to a method for diagnosing Farber's disease in a subject, wherein the method comprises detecting C26 ceramide in a sample from the subject.

Method for the diagnosis of Farber's disease

The present invention is related to an in vitro method for diagnosing Gaucher's disease in a subject comprising a step of

Method for the diagnosis of Gaucher's disease

The present invention is related to an in vitro method for diagnosing Gaucher's disease in a subject comprising a step of a) detecting a biomarker in a sample from the subject, wherein the biomarker is free lyso-Gb1.

The present invention is related to a method for diagnosing metachromatic leukodystrophy in a subject comprising a step a), wherein the step a) comprises detecting a biomarker in a sample from the subject, wherein the sample is selected from the group consisting of blood, dried blood, serum and plasma and wherein the biomarker is different from an enzyme.

Method for the diagnosis of metachromatic leukodystrophy

The present invention is related to a method for diagnosing Niemann-Pick disease in a subject comprising a step a), wherein the step a) comprises detecting a biomarker in a sample from the subject, wherein the biomarker is compound 509.

The present invention is related to a compound of formula (I) a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, a metabolite thereof or a prodrug thereof; for use in a method for the treatment and/or prevention of cancer, wherein X is selected from the group consisting of N&#x2014;R, O and S; R1 is selected from the group consisting of alkyl, cycloalkyl, aryl, arylalkyl and hydrogen; Ris selected from the group consisting of indolyl, substituted indolyl, azaindolyl and substituted azaindolyl; and Ris selected from the group consisting of aryl, substituted aryl, unsubstituted heteroaryl, heterocyclyl and substituted heterocyclyl. 

Use of maleimide derivatives for preventing and treating cancer

The present invention is related to a method for diagnosing Niemann-Pick disease in a subject comprising a step a), wherein the step a) comprises detecting a biomarker in a sample from the subject.

The present invention is related to a compound of formula (I): a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, a metabolite thereof or a prodrug thereof; for use in a method for the treatment and/or prevention of leukemia, wherein X is selected from the group consisting of N&#x2014;R, O and S; Ris selected from the group consisting of alkyl, cycloalkyl, aryl, arylalkyl and hydrogen; Ris selected from the group consisting of indolyl, substituted indolyl, azaindolyl and substituted azaindolyl; and Ris selected from the group consisting of aryl, substituted aryl, unsubstituted heteroaryl, heterocyclyl and substituted heterocyclyl. 

Use of maleimide derivatives for preventing and treating leukemia

A kit and a nucleic acid molecule primer and/or probe for the analytical detection ofare disclosed. The detection employs nucleic acid amplification and/or nucleic acid hybridization.

[object Object]

The present invention relates to a nucleic acid molecule or molecules and to a process for the detection of bacteria of thegenus, especially. The invention relates also to a test kit or kits for carrying out the said detection processes.

Amino acid sequences and method for isolating bacteries from the type genus pseudomonas

Method for the genus-specific amplification of legionella and genus-specific or species-specific identification.

Growing community of inventors

Berlin, Germany

Arndt Rolfs