Basf Aktiengesellschaft

Basf Se Corporation

Armin Stamm

Jochem Henkelmann

Theodor Weber

Heinz-Josef Kneuper

Bernd Wolf

Hans-J&uuml;rgen Weyer

Thorsten Rohde

Michael Keil

Wolfgang Siegel

Alfred Oftring

Heinz-Peter Rink

Norbert G&ouml;tz

Roland G&ouml;tz

Thomas Schmidt

Michael Henningsen

Heiko Maas

Marta Reinoso Garcia

Werner-Alfons Jung

Gerold Braun

Michael Klemens Mueller

Frank Jaekel

Adrian Steinmetz

Constanze Franzke

Friedrich Wirsing

Ralph Busch

Winfried M&uuml;ller

Jeremy T Manning

Robert Baumann

Martin Fischer

Manfred Julius

Peter Schwab

Alois Kindler

Stefan Rittinger

Norbert Götz

Manfred Niessner

Kai-Uwe Baldenius

Gerhard Schulz

Markus Hartmann

Primoz Lorencak

Sabine Weiguny

Jakob Fischer

Verena Mormul

Axel Franzke

Carsten Sueling

J&ouml;rg Botzem

Manfred Heilig

Lucien Thil

Hans-Jurgen Weyer

Roland Götz

Jens Utecht

Hans-Peter Schildberg

Peter Dransfeld

Christopher Orr

Eckhard Schwartz

Daniel Dan-Tam Tang

Jeremy Manning

Roland GÖTZ

The present invention is directed towards a process for manufacturing a complexing agent, said process comprising the steps of (a) Providing a nitrile according to general formula (I a) or (I b)  With M being selected from alkali metal and hydrogen and combinations thereof, (b) Saponification with a total alkali amount of 2.5 to 2.9 mol of alkali metal hydroxide per mole of nitrile according to general formula (I a) or (I b), respectively, and a pH value in the range of from 9.5 to 11.5 at the end of step (b), (c) Adding an amount of alkali metal hydroxide so that the total alkali content is 2.9 to 3.15 moles per mole nitrile according to general formula (I a) or (I b), respectively, and (d) Allowing further conversion.

Process for manufacturing a complexing agent

Process for making a powder or granule containing at least one chelating agent selected from alkali metal salts of methyl glycine diacetic acid (MGDA) and glutamic acid diacetate (GLDA) and iminodisuccinic acid (IDS), said process comprising the steps of (a) introducing an aqueous solution or aqueous slurry of the respective chelating agent (A) into a spray-dryer or spray-granulator, and removing most of said water by spray-drying or spray granulation using a gas with an inlet temperature of 125 to 250&#xb0; C., (b) withdrawingpowder or granules, respectively, from the spray-dryer or spray-granulator, respectively, (c) separating off fines from said powder or granules, wherein said fines have a maximum particle diameter of 350 &#x3bc;m, (d) separating off lumps from said powder or granules, wherein said lumps have a particle diameter of 1,500 &#x3bc;m or more, (e) milling said lumps to a maximum particle diameter of 500 &#x3bc;m, (f) re-introducing said fines from step (c) and milled lumps from step (e) into the spray-dryer or spray-granulator, wherein the share of fines is in the range of from 0.5 to 20% by weight of the total chelating agent (A) withdrawn in step (b) and the share of milled lumps is in the range of from 5 to 60% by weight of the total chelating agent (A) withdrawn in step (b).

Powders and granules and process for making such powders and granules

Process for making a chelating agent according to the general formula (I), R&#x2014;CH(COOX)&#x2014;N(CH2COOX)wherein Ris selected from hydrogen, C-C-alkyl, phenyl, benzyl, CHOH, and CHCHCOOX, Xis (MH), M being selected from alkali metal, x is in the range of from 0.6 to 1, said process comprising the following steps: (a) providing a solid, a slurry or a solution of a compound according to general formula (II a) R&#x2014;CH(COOX)&#x2014;N(CHCN)wherein Xis (MH), M being selected from alkali metal, y is in the range of from zero to 1, (b) contacting said solid or slurry or solution with an aqueous solution of alkali metal hydroxide, wherein the molar ratio of alkali metal ions to nitrile groups is in the range of from 0.6:1 to 0.95:1, (c) reacting said compound according to general formula (II a) with said alkali metal hydroxide.

Process for making mixtures of chelating agents

Process for manufacturing a crystalline alkali metal salt of the general formula (I) [R&#x2014;CH(COO)&#x2014;N(CH&#x2014;COO)]M(I) wherein Mis selected from alkali metal cations, same or different, Ris selected from C-C-alkyl and CHCHCOOM, comprising the step of (b) crystallizing said alkali metal salt from an aqueous solution containing in the range of from 5 to 30% by weight of alkali metal hydroxide, referring to said aqueous solution.

Process for making a crystalline alkali metal salt of a complexing agent, and crystalline complexing agent

Aqueous solution containing in the range of from 60.5 to 75% by weight of a mixture of trialkalimetal salts of the L-and D-enantiomers of methyl glycine diacetic acid (MGDA), said mixture containing predominantly the respective L-isomer with an enantiomeric excess (ee) in the range of from 3 to 97%, wherein said trialkali metal salts have the general formula (I) [CH&#x2014;CH(COO)&#x2014;N(CH&#x2014;COO)]KNa(I) wherein x is in the range of from zero to 2.9.

Solutions of trialkali metal salts of MGDA with an excess of L-enantiomer, their manufacture and use

Provided is a method for the production of aminodicarboxylic acid N,N-diacetic acids of formula (I), wherein X is independently hydrogen or an alkali metal and n is 1 or 2. Aminodicarboxylic acid-N,N-diacetic acids of high purity can be yielded. The method involves: a) reacting an aminodicarboxylic acid, with 0.8 to 1.2 mole equivalents of formaldehyde and with 0.8 to 1.2 mole equivalents of hydrocyanic acid; b) reacting the reaction products of a) with 0.8 to 1.2 mole equivalents of hydrocyanic acid and with 0.8 to 1.2 mole equivalents of formaldehyde; c) hydrolyzing in the reaction product obtained in b).

Method for the production of aminodicarboxylic acid-N,N-diacetic acids

The invention relates to a process for preparing low-by-product, light-color methylglycine-N,N-diacetic acid tri(alkali metal) salt by alkaline hydrolysis of methylglycinediacetonitrile (MGDN), comprising the steps in the sequence (a) to (f):

Method for producing methylglycine-N,N-diethanoic acid-trialkali metal salts with a low by-product content

In a process for preparing isocyanates by reacting the corresponding primary amines with phosgene in an inert solvent, use is made of from 0.01 to 50 mol % of a phosphine oxide, based on the total amount of primary amine and isocyanate formed in the reaction solution.

Method for producing isocyanates

In a process for preparing isocyanates by reacting the corresponding primary amines with phosgene in an inert solvent, use is made of from 0.01 to 50 mol % of a sulfonamide, based on the total amount of primary amine and isocyanate formed in the reaction solution.

Method for production of isocyanates

A method is provided for the intrinsically safe handling of 3-chloropropyne in the presence of a diluent with a boiling point ranging from &#x2212;50&#xb0; C. (223 K) to 200&#xb0; C. (473 K) under atmospheric pressure, wherein the concentration of 3-chloropropyne in the liquid phase and in the gas phase is kept below the concentrations capable of deflagration by means of the type and amount of the diluent, the temperature and the total system pressure, together with the use of a 3-chloropropyne prepared, stored or transported in this way in the synthesis of dyestuffs, pharmaceutical and agricultural active ingredients, electroplating auxiliaries, disinfectants, steroids and growth hormones.

Method for the intrinsically safe handling of 3-chloropropyne

In a process for preparing isocyanates by reacting the corresponding primary amines with phosgene in an inert solvent, use is made of from 0.01 to 50 mol % of a sulfoxide, a sulfone or a mixture thereof, based on the total amount of primary amine and isocyanate formed in the reaction solution.

The invention relates to a method for producing o-chloromethyl benzoic acid chlorides of formula (I), in which Rto Rcan be the same or different and represent hydrogen C&#x2013;Calkyl, halogen or trifluoromethyl, by reaction benzo condensed lactones of formula (II), in which Rto Rhave the above-mentioned meaning, with thionyl chloride. The inventive method is characterized in that the reaction is carried out in the presence of catalytic quantities of a Lewis acid and in the presence of catalytic quantities of a phosphine derivative.

Method for producing o-chloromethyl benzoic acid chlorides

In a process for preparing carbonyldiimidazole from imidazole and phosgene in an inert solvent, the imidazole hydrochloride which results as coupled product is removed as melt from the resulting reaction mixture by phase separation.

Method for producing carbonyldiimidazole

The invention relates to a method for producing acid chlorides by converting carboxylic acids with carbon oxychlorides or thionyl chloride in the presence of a catalyst adduct of an N,N-disubstituted formamide of general formula (I) and carbon oxychloride or thionyl chloride. In the formula, R and R , independently from one another, mean C - to C -alkyl or R and R together mean a C - or C -alkylene chain. According to the inventive method, hydrogen chloride is added during and/or after the conversion.

Method for producing acid chlorides

Polyisocyanates as coating components for coating means rich in solids

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Nieder-Olm, Germany

Armin Stamm